Effect of comprehensive nursing intervention on negative emotion, quality of life and renal function of hemodialysis patients

Objective: To explore the effects of comprehensive nursing intervention on negative emotion, quality of life and renal function of hemodialysis patients. Methods: A total of 128 patients with chronic renal failure or end-stage renal disease who underwent hemodialysis were randomly divided into conventional care group and comprehensive nursing group according to the nursing care methods. The comprehensive nursing group received cognitive behavioral therapy and extended care in addition to conventional care. The changes of self-rating anxiety scale (SAS) scores, self-rating depression scale (SDS) scores, quality of life (the Kidney Disease Quality of Life-36 questionnaire, KDQOL-36TM) scores at admission and three months after discharge, as well as changes in creatinine clearance rates (Ccr) and effective urea clearance volume of distribution of urea/effective dialysis time (KT/V) were recorded and compared between the two groups. Results: The differences of Ccr and KT/V before and after intervention between the comprehensive nursing group and the conventional care group were 3.96 +/- 4.78 mL/min/1.73 m(2), 2.32 +/- 2.89 mL/min/1.73 m(2) and 0.41 +/- 0.62 mL/min/1.73 m(2), 0.18 +/- 0.29 mL/min/1.73 m(2) respectively. The difference values of the comprehensive nursing group were significantly higher than those in the conventional care group (all P<0.05). In addition, the comprehensive nursing group also had significantly higher difference values in SAS, SDS and quality of life (QOL) scores compared to the conventional care group (all P<0.05). Conclusion: Comprehensive nursing interventions can effectively alleviate anxiety and depression of hemodialysis patients and improve their quality of life and renal function.