Prehospital therapeutic hypothermia after cardiac arrest - from current concepts to a future standard

被引：12

作者：

Kamarainen, Antti ^{[1
,2
]}

Hoppu, Sanna ^{[1
,3
]}

Silfvast, Tom ^{[2
]}

Virkkunen, Ilkka ^{[4
]}

机构：

[1] Tampere Univ Hosp, Dept Intens Care Med, Crit Care Med Res Grp, Tampere, Finland

[2] Helsinki Univ Hosp, Dept Anaesthesia & Intens Care, Helsinki, Finland

[3] Univ Tampere, Fac Med, FIN-33101 Tampere, Finland

[4] Tampere Univ Hosp, Dept Surg & Anaesthesia, Tampere, Finland

来源：

SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE | 2009年 / 17卷

关键词：

ADVANCED LIFE-SUPPORT; COMATOSE SURVIVORS; MILD HYPOTHERMIA; COLD SALINE; RESUSCITATION; INDUCTION; FEASIBILITY; MODEL; TRIAL; INFUSION;

D O I：

10.1186/1757-7241-17-53

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Therapeutic hypothermia has been shown to improve survival and neurological outcome after prehospital cardiac arrest. Existing experimental and clinical evidence supports the notion that delayed cooling results in lesser benefit compared to early induction of mild hypothermia soon after return of spontaneous circulation. Therefore a practical approach would be to initiate cooling already in the prehospital setting. The purpose of this review was to evaluate current clinical studies on prehospital induction of mild hypothermia after cardiac arrest. Most reported studies present data on cooling rates, safety and feasibility of different methods, but are inconclusive as regarding to outcome effects.

引用

页数：6

共 33 条

[1] Intra-arrest cooling improves outcomes in a murine cardiac arrest model [J].