Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex

被引：69

作者：

Lin, Bo-Nan ^{[1
]}

Huang, Shao-Hsien ^{[1
]}

Wu, Wei-Yi ^{[1
]}

Mou, Chung-Yuan ^{[2
]}

Tsai, Fu-Yu ^{[1
]}

机构：

[1] Natl Taipei Univ Technol, Inst Organ & Polymer Mat, Taipei 106, Taiwan

[2] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan

来源：

MOLECULES | 2010年 / 15卷 / 12期

关键词：

Sonogashira reaction; mesoporous silica; palladium complex; recyclable catalyst; heterogeneous catalysis; CROSS-COUPLING REACTIONS; HETEROCYCLIC CARBENE COMPLEXES; COPPER-FREE; MESOPOROUS MATERIALS; PROPARGYL ALCOHOLS; HECK; PD/C; SUZUKI; SILICA; PALLADACYCLES;

D O I：

10.3390/molecules15129157

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A heterogeneous catalyst, nanosized MCM-41-Pd, was used to catalyze the Sonogashira coupling of aryl and heteroaryl halides with terminal alkynes in the presence of CuI and triphenylphosphine. The coupling products were obtained in high yields using low Pd loadings to 0.01 mol%, and the nanosized MCM-41-Pd catalyst was recovered by centrifugation of the reaction solution and re-used in further runs without significant loss of reactivity.

引用

页码：9157 / 9173

页数：17

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