Solvent-Free Microwave Extraction of Thymus mastichina Essential Oil: Influence on Their Chemical Composition and on the Antioxidant and Antimicrobial Activities

被引：16

作者：

Araujo, Andre R. T. S. ^{[1
,2
]}

Perino, Sandrine ^{[3
]}

Fernandez, Xavier ^{[4
]}

Cunha, Cassandra ^{[1
]}

Rodrigues, Marcio ^{[1
,5
]}

Ribeiro, Maximiano P. ^{[1
,5
]}

Jordao, Luisa ^{[6
]}

Silva, Lucia A. ^{[7
]}

Rodilla, Jesus ^{[7
]}

Coutinho, Paula ^{[1
,5
]}

Chemat, Farid ^{[3
]}

机构：

[1] Polytech Inst Guarda, Res Unit Inland Dev UDI, Av Dr Francisco Sa Carneiro 50, P-6300559 Guarda, Portugal

[2] Univ Porto, Fac Pharm, Dept Chem Sci, LAQV REQUIMTE, Rua Jorge Viterbo Ferreira 228, P-4050313 Porto, Portugal

[3] Avignon Univ, GREEN Extract Team, INRAE, UMR 408, F-84000 Avignon, France

[4] Univ Cote Azur, CNRS, ICN, Parc Valrose, F-06108 Nice 2, France

[5] Univ Beira Interior, CICS, UBI, Hlth Sci Res Ctr, Av Infante D Henrique, P-6200506 Covilha, Portugal

[6] Natl Inst Hlth Doutor Ricardo Jorge, Res & Dev Unit, Dept Environm Hlth, Ave Padre Cruz, P-1649016 Lisbon, Portugal

[7] Univ Beira Interior, FibEnTech Fiber Mat & Environm Technol, Dept Chem, Fac Sci, Rua Marques Avila & Bolama, P-6201001 Covilha, Portugal

来源：

PHARMACEUTICALS | 2021年 / 14卷 / 08期

关键词：

essential oil; green extraction; large scale; solvent-free microwave extraction; Thymus mastichina; AROMATIC HERBS; HYDRODISTILLATION; LAMIACEAE;

D O I：

10.3390/ph14080709

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Solvent-free microwave extraction (SFME) is a combination of microwave heating and dry distillation performed at atmospheric pressure without the addition of water or organic solvents that has been proposed as a green method for the extraction of essential oils from aromatic and medicinal herbs. In this work, SFME and the conventional techniques of steam distillation (SD) and hydrodistillation (HD) were compared with respect to the extraction and antioxidant and antimicrobial activities of Thymus mastichina essential oil. The main constituent of essential oils obtained using different methods was 1,8-cineole (eucalyptol). The results showed that the essential oils extracted by means of SFME in 30 min were quantitatively (yield) and qualitatively (aromatic profile) similar to those obtained using conventional HD over 120 min. In addition, SFME generates less waste and less solvent, consumes less energy, and provides a higher yield for a shorter extraction time, which is advantageous for the extraction of the T. mastichina essential oil compared to SD. The antioxidant and antimicrobial activities of the T. mastichina essential oil obtained from either SFME or conventional extraction methods (SD or HD) showed a similar pattern. Large-scale experiments using this SFME procedure showed a potential industrial application.

引用

页数：13

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