Dehydration confounds the assessment of brain atrophy

被引：147
作者：
Duning, T
Kloska, S
Steinsträter, O
Kugel, H
Heindel, W
Knecht, S
机构：
[1] Univ Munster, Dept Neurol, D-48129 Munster, Germany
[2] Univ Munster, Dept Clin Radiol, D-48129 Munster, Germany
来源：
NEUROLOGY | 2005年 / 64卷 / 03期
关键词：
D O I：
10.1212/01.WNL.0000150542.16969.CC
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Computerized brain volumetry has potential value for diagnosis and the follow-up evaluation of degenerative disorders. A potential pitfall of this method is the extent of physiologic variations in brain volume. The authors show that dehydration and rehydration can significantly change brain volume: lack of fluid intake for 16 hours decreased brain volume by 0.55% (SD, +/-0.69), and after rehydration total cerebral volume increased by 0.72% (SD, +/-0.21).
引用
收藏
页码：548 / 550
页数：3
相关论文
共 10 条
[1]   Neuroimaging of cerebral and cerebellar atrophy in anorexia nervosa [J].
Addolorato, G ;
Taranto, C ;
De Rossi, G ;
Gasbarrini, G .
PSYCHIATRY RESEARCH-NEUROIMAGING, 1997, 76 (2-3) :139-141
[2]   Fluid and electrolytes in the elderly [J].
Allison, SP ;
Lobo, DN .
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2004, 7 (01) :27-33
[3]   Aquaporins in brain: Distribution, physiology, and pathophysiology [J].
Badaut, T ;
Lasbennes, T ;
Magistretti, PJ ;
Regli, L .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2002, 22 (04) :367-378
[4]   Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging [J].
Chetelat, G ;
Baron, JC .
NEUROIMAGE, 2003, 18 (02) :525-541
[5]   Accelerated evolution of brain atrophy and "Black holes" in MS patients with APOE-ε4 [J].
Enzinger, C ;
Ropele, S ;
Smith, S ;
Strasser-Fuchs, S ;
Poltrum, B ;
Schmidt, H ;
Matthews, PM ;
Fazekas, F .
ANNALS OF NEUROLOGY, 2004, 55 (04) :563-569
[6]   Brain atrophy progression measured from registered serial MRI: Validation and application to Alzheimer's disease [J].
Fox, NC ;
Freeborough, PA .
JOURNAL OF MAGNETIC RESONANCE IMAGING, 1997, 7 (06) :1069-1075
[7]   Structural imaging in the clinical diagnosis of Alzheimer's disease: problems and tools [J].
Frisoni, GB .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2001, 70 (06) :711-718
[8]   Accurate, robust, and automated longitudinal and cross-sectional brain change analysis [J].
Smith, SM ;
Zhang, YY ;
Jenkinson, M ;
Chen, J ;
Matthews, PM ;
Federico, A ;
De Stefano, N .
NEUROIMAGE, 2002, 17 (01) :479-489
[9]   Thirst [J].
Stricker, EM ;
Sved, AF .
NUTRITION, 2000, 16 (10) :821-826
[10]   MR image-based measurement of rates of change in volumes of brain structures. Part 1: Method and validation [J].
Wang, DM ;
Doddrell, DM .
MAGNETIC RESONANCE IMAGING, 2002, 20 (01) :27-40
1