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Role of Flavonoids in Neurodegenerative Disorders with Special Emphasis on Tangeritin
被引:11
|作者:
Fatima, Ambreen
[1
]
Siddique, Yasir Hasan
[1
]
机构:
[1] Aligarh Muslim Univ, Fac Life Sci, Dept Zool, Drosophila Transgen Lab,Sect Genet, Aligarh, Uttar Pradesh, India
关键词:
Flavanoids;
tangeritin;
neurodegeneration;
biosynthetic pathway;
polyphenols;
flavones;
NEURONAL SIGNAL-TRANSDUCTION;
FATTY LIVER-DISEASE;
CELL-CYCLE ARREST;
ANTIOXIDANT ACTIVITY;
DIETARY FLAVONOIDS;
POLYMETHOXYLATED FLAVONES;
MICROGLIAL ACTIVATION;
METHYLATED FLAVONOIDS;
FLAVANONE GLYCOSIDES;
TRANSCRIPTION FACTOR;
D O I:
10.2174/1871527318666190916141934
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
Flavonoids are naturally occurring plant polyphenols found universally in all fruits, vegetables and medicinal plants. They have emerged as a promising candidate in the formulation of treatment strategies for various neurodegenerative disorders. The use of flavonoid rich plant extracts and food in dietary supplementation have shown favourable outcomes. The present review describes the types, properties and metabolism of flavonoids. Neuroprotective role of various flavonoids and the possible mechanism of action in the brain against the neurodegeneration have been described in detail with special emphasis on the tangeritin.
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页码:581 / 597
页数:17
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