Tropheryma whipplei in the skin of patients with classic Whipple's disease

被引:17
作者
Angelakis, Emmanouil [1 ]
Fenollar, Florence [1 ]
Lepidi, Hubert [1 ]
Birg, Marie-Laure [1 ]
Raoult, Didier [1 ]
机构
[1] Univ Aix Marseille 2, Unite Rickettsies, URMITE CNRS IRD UMR 6236, Fac Med, F-13385 Marseille 05, France
关键词
Whipple's disease; Tropheryma whipplei; Skin biopsy; qPCR; RECONSTITUTION INFLAMMATORY SYNDROME; SPECIMENS; DIAGNOSIS; CULTURE; STOOL;
D O I
10.1016/j.jinf.2010.06.007
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Positive Tropheryma whipplei PCR results in skin biopsies were frequent in patients with classic Whipple's disease without skin manifestations. The bacterium was alive, as a strain was successfully cultured. The skin may be a reservoir for T. whipplei and may be helpful in the non-invasive diagnosis of the disease. (C) 2010 The British Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:266 / 269
页数:4
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