New potent and selective human adenosine A3 receptor antagonists

[1] The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-xL:: Studies in human astroglioma cells [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 241 (02) : 297 - 304

[2] Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]-pyrimidine derivatives as highly potent and selective human A3 adenosine receptor antagonists [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (22) : 4473 - 4478

[3] Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5′-N-ethyluronamide as A1 and A3 adenosine receptor agonists [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (17) : 3174 - 3185

[4] Novel N-6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A(3) adenosine receptors [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (03) : 802 - 806

[5] Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine:: involvement of A3 adenosine receptor [J]. JOURNAL OF LEUKOCYTE BIOLOGY, 1999, 66 (03) : 495 - 501

[6] 1,2,4-triazolol[4,3-a]quinoxalin-1-one:: A versatile tool for the synthesis of potent and selective adenosine receptor antagonists [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (06) : 1158 - 1164

[7] Adenosine A3 receptors on human eosinophils mediate inhibition of degranulation and superoxide anion release [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1999, 127 (01) : 188 - 194

[8] Adenosine, mast cells and asthma [J]. INFLAMMATION RESEARCH, 1999, 48 (06) : 301 - 307

[9] FREDHOLM BB, 1994, PHARMACOL REV, V46, P143

[10] Adenosine A3 receptors:: novel ligands and paradoxical effects [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1998, 19 (05) : 184 - 191

[1] The A3 adenosine receptor mediates cell spreading, reorganization of actin cytoskeleton, and distribution of Bcl-xL:: Studies in human astroglioma cells [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1997, 241 (02) : 297 - 304

[2] Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]-pyrimidine derivatives as highly potent and selective human A3 adenosine receptor antagonists [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1999, 42 (22) : 4473 - 4478

[3] Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5′-N-ethyluronamide as A1 and A3 adenosine receptor agonists [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (17) : 3174 - 3185

[4] Novel N-6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A(3) adenosine receptors [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (03) : 802 - 806

[5] Inhibition of fMLP-triggered respiratory burst of human monocytes by adenosine:: involvement of A3 adenosine receptor [J]. JOURNAL OF LEUKOCYTE BIOLOGY, 1999, 66 (03) : 495 - 501

[6] 1,2,4-triazolol[4,3-a]quinoxalin-1-one:: A versatile tool for the synthesis of potent and selective adenosine receptor antagonists [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (06) : 1158 - 1164

[7] Adenosine A3 receptors on human eosinophils mediate inhibition of degranulation and superoxide anion release [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1999, 127 (01) : 188 - 194

[8] Adenosine, mast cells and asthma [J]. INFLAMMATION RESEARCH, 1999, 48 (06) : 301 - 307

[9] FREDHOLM BB, 1994, PHARMACOL REV, V46, P143

[10] Adenosine A3 receptors:: novel ligands and paradoxical effects [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 1998, 19 (05) : 184 - 191