Accurate image segmentation based on adaptive distance regularization level set method

Level set method has been widely applied in the field of image segmentation. However, the level set formulation is inevitably affected by the regularization function, in-homogeneity and weak edge in the process of evolution, which often leads to the instability and inaccuracy of image segmentation results. To solve these problems, a new distance regularization term defined by a double-well potential function is proposed to satisfy more ideal characteristics of signed distance property. In addition, a novel edge indicator function is introduced to segment images with uneven intensity or weak edge. Finally, the adaptive adjustment formulas of distance regularization and area parameters are derived to alleviate the difficulty of parameter adjustment. Experimental results show that the proposed model provides better accuracy and versatility, quantitative experiment on Weizmann segmentation evaluation database achieves mean Dice score (96.87%), IoU (94.38%), Hausdorff distance (3.20 mm), Recall (97.68%) and Precision (96.32%), respectively.