Langerhans Cell Histiocytosis of the Petrous Bone With Sudden Sensorineural Hearing Loss

被引：6

作者：

Suzuki, Hideaki ^{[1
]}

Nishizawa, Shigeru ^{[2
]}

Hohchi, Nobusuke ^{[1
]}

Wakasugi, Tetsuro ^{[1
]}

Shibata, Minori ^{[1
]}

Ohkubo, Jun-ichi ^{[1
]}

Tsukada, Jun-ichi ^{[3
]}

机构：

[1] Univ Occupat & Environm Hlth, Sch Med, Dept Otorhinolaryngol, Yahatanishi Ku, Kitakyushu, Fukuoka 8078555, Japan

[2] Univ Occupat & Environm Hlth, Sch Med, Dept Neurosurg, Kitakyushu, Fukuoka 8078555, Japan

[3] Univ Occupat & Environm Hlth, Sch Med, Ctr Canc Chemotherapy, Kitakyushu, Fukuoka 8078555, Japan

来源：

NEUROLOGIA MEDICO-CHIRURGICA | 2010年 / 50卷 / 08期

关键词：

Langerhans cell histiocytosis; temporal bone; petrous bone; imaging examination; sudden sensorineural hearing loss; EOSINOPHILIC GRANULOMA; TEMPORAL BONE; FOLLOW-UP; DIAGNOSIS; CLIVUS; APEX;

D O I：

10.2176/nmc.50.693

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 56-year-old woman with Langerhans cell histiocytosis of the petrous bone presented with sudden onset of sensorineural hearing loss and vertigo without other neurological impairment, mimicking idiopathic sudden sensorineural hearing loss. Differential diagnosis was difficult until neuroimaging demonstrated a lesion of the petrous bone. The patient eventually underwent removal of the lesion via the transpetrosal approach, and received postoperative chemotherapy consisting of vinblastine, methotrexate, 6-mercaptopurine, and prednisolone. Although her hearing did not recover, complete remission was achieved, and the patient is currently free from disease. Physicians need to be aware that patients with sudden onset of hearing loss may have an unexpected and hidden disease which requires neuroimaging and histological examinations for definitive diagnosis and appropriate treatment.

引用

页码：693 / 697

页数：5

共 22 条

[1]

ANONSEN CK, 1987, LARYNGOSCOPE, V97, P537

[2] HISTIOCYTOSIS-X OF THE PETROUS BONE IN THE ADULT - MRI [J].