Hypogonadotropic hypogonadism in Klinefelter syndrome and hypothalamic-pituitary tumor

被引：0
作者：
Beisti Ortego, Anunciacion [1 ]
De Arriba Munoz, Antonio [1 ]
Lozano, Marta Ferrer [1 ]
de Zabarte Fernandez, Jose Miguel Martinez [1 ]
Calvo Escribano, Carlota [1 ]
Labarta Aizpun, Jose Ignacio [1 ]
机构：
[1] Hosp Univ Miguel Servet, Zaragoza, Spain
来源：
ARCHIVOS ARGENTINOS DE PEDIATRIA | 2015年 / 113卷 / 01期
关键词：
Klinefelter Syndrome; hypogonadism; germ cell tumors; GERM-CELL TUMORS; CANCER INCIDENCE; MEN; ASSOCIATION;
D O I：
10.5546/aap.2015.e6
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Klinefelter Syndrome is the most frequent cause of hypergonadotropic hypogonadism in men. A flat response at luteinizing hormone releasing hormone stimulation test could be the first sign of hypothalamic tumor in these patients. We report the case of a patient diagnosed by neonatal screening with Klinefelter Syndrome, 47 XXY, that at 17 years follow-up presents analytical modification of the response to luteinizing hormone releasing hormone stimulation test with suppressed luteinizing hormone and follicle-stimulating hormone values; lately he presents with headache and loss of left eye vision. A magnetic resonance imaging of the brain showed a mixed germ cell hypothalamus tumor, requiring surgery, chemotherapy and radiotherapy with optimal response.
引用
收藏
页码：E6 / E9
页数：4
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