Cellular fluorescence imaging based on resonance energy transfer

被引:26
作者
Zhang, Wei [1 ]
Liu, Xiaolei [1 ]
Li, Ping [1 ]
Zhang, Wen [1 ]
Wang, Hui [1 ]
Tang, Bo [1 ]
机构
[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Collaborat Innovat Ctr Functionalized Probes Chem, Key Lab Mol & Nano Probes,Minist Educ,Inst Biomed, Jinan 250014, Peoples R China
基金
中国国家自然科学基金;
关键词
Fluorescence imaging; Cells; Resonance energy transfer; Active small molecules; Fluorescent probe; BIO-MOLECULAR EVENTS; IN-VITRO; REACTIVE OXYGEN; QUANTUM DOTS; LIVING CELLS; CARBON DOTS; HG2+ SENSOR; FRET; PROBE; BODIPY;
D O I
10.1016/j.trac.2019.115742
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Fluorescence imaging of intracellular active molecules plays an important role in understanding the occurrence and development of diseases. Resonance energy transfer (RET) has been recognized as a powerful technology in the design of fluorescence probes for biological imaging. Here, we summarize the novel approaches to fabrication of RET-based fluorescent probes systems such as the organic molecular fluorescent probe, nano fluorescent probe, protein probe and their recent applications in cellular fluorescence imaging. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页数:13
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