The myth of lanolin allergy

被引:39
作者
Kligman, AM [1 ]
机构
[1] Univ Penn, Sch Med, Dept Dermatol, Philadelphia, PA 19104 USA
关键词
wool wax alcohols; lanolin allergy; contact sensitization to lanolin; patch testing technique; false-positive reactions;
D O I
10.1111/j.1600-0536.1998.tb05856.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Lanolin has the reputation of being an important contact sensitizer. The market place abounds with products that are labeled "lanolin free". In fact, lanolin is at most a weak contact allergen. The supposed hazards of sensitization to lanolin products are a resultant of faulty science and failure to appreciate the limitations of patch testing. Lanolin allergy is a myth created mainly by overzealous professional patch testers. No one has succeeded in sensitizing animals or humans to lanolin or wool wax alcohols. Most of the case reports are false positives, in association with the angry back syndrome.
引用
收藏
页码:103 / 107
页数:5
相关论文
共 29 条
[1]  
ANDERSEN KE, 1995, TXB CONTACT DERMATIT, P435
[2]  
[Anonymous], 1980, CONTACT DERMATITIS
[3]   DERMATITIS FROM APPLIED MEDICAMENTS [J].
BANDMANN, HJ ;
CALNAN, CD ;
WILKINSON, DS ;
CRONIN, E ;
MAIBACH, H ;
MAGNUSSON, B ;
FREGERT, S ;
HJORTH, N ;
MALTEN, KE ;
MENEGHINI, CL ;
PIRILA, V .
ARCHIVES OF DERMATOLOGY, 1972, 106 (03) :335-+
[4]  
BONNEVIE P, 1939, NYT NORDESK FORLAG, P354
[5]  
BRAUN W, 1970, MED KLIN, V65, P2
[6]  
CARMICHAEL AJ, 1991, CONTACT DERMATITIS, V23, P271
[7]   LANOLIN WITH REDUCED SENSITIZING POTENTIAL - PRELIMINARY NOTE [J].
CLARK, EW ;
WILKINSON, DS .
CONTACT DERMATITIS, 1977, 3 (02) :69-74
[8]   LANOLIN OF REDUCED SENSITIZING POTENTIAL [J].
CLARK, EW ;
BLONDEEL, A ;
CRONIN, E ;
OLEFFE, JA ;
WILKINSON, DS .
CONTACT DERMATITIS, 1981, 7 (02) :80-83
[9]  
CLARK EW, 1975, J SOC COSMET CHEM, V26, P323
[10]   TESTING A PURIFIED LANOLIN PREPARATION BY A RANDOMIZED PROCEDURE [J].
EDMAN, B ;
MOLLER, H .
CONTACT DERMATITIS, 1989, 20 (04) :287-290