Visualization of Nitroxyl in Living Cells by a Chelated Copper(II) Coumarin Complex

被引：142
作者：
Zhou, Yi
Liu, Ke
Li, Ju-Ying
Fang, Yuan
Zhao, Tian-Chu
Yao, Cheng [1 ]
机构：
[1] Nanjing Univ Technol, State Key Lab Mat Oriented Chem Engn, Nanjing 210009, Peoples R China
来源：
ORGANIC LETTERS | 2011年 / 13卷 / 06期
关键词：
NITRIC-OXIDE PRODUCTION; AQUEOUS-SOLUTION; FLUORESCENT-PROBES; IN-VIVO; SENSOR; CYCLOADDITION; CHEMISTRY; DESIGN;
D O I：
10.1021/ol103077q
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on the basis of the reduction reaction. In addition, highly selective "turn on" type fluorogenic behavior upon the addition of Angeli's salt (Na2N2O3) was also applied to bioimaging in A375 cells.
引用
收藏
页码：1290 / 1293
页数：4
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