Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review

被引：18

作者：

Nel, Jeremy S. ^{[1
]}

Lippincott, Christopher K. ^{[2
]}

Berhanu, Rebecca ^{[3
]}

Spencer, David C. ^{[4
]}

Sanne, Ian M. ^{[5
]}

Ive, Prudence ^{[1
]}

机构：

[1] Univ Witwatersrand, Fac Hlth Sci, Helen Joseph Hosp, Div Infect Dis,Dept Internal Med, Johannesburg, South Africa

[2] Johns Hopkins Univ, Sch Med, Div Infect Dis, Baltimore, MD 21205 USA

[3] Univ N Carolina, Ctr Infect Dis, Chapel Hill, NC USA

[4] Right Care, Johannesburg, South Africa

[5] Univ Witwatersrand, Fac Hlth Sci, Sch Clin Med, Clin HIV Res Unit,Dept Internal Med, Johannesburg, South Africa

来源：

CLINICAL INFECTIOUS DISEASES | 2017年 / 65卷 / 07期

关键词：

Determine TB-LAM; lipoarabinomannan; nontuberculous mycobacteria; tuberculosis; LIPOARABINOMANNAN; URINE; TUBERCULOSIS; HIV;

D O I：

10.1093/cid/cix513

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We retrospectively reviewed the Determine TB-LAM lateral flow assay (LF-LAM) results among human immunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease. LF-LAM was positive in 19 of 21 patients without evidence of tuberculosis (TB) coinfection. Although TB-NTM coinfection may have been underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM results.

引用

页码：1226 / 1228

页数：3

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