A chiral ketone for enantioselective recognition of 1,2-amino alcohols

被引：15
|
作者：
Nandhakumar, Raju
Guo, Yong-En
Park, Hytinjung
Tang, Lijun
Nam, Wonwoo
Kim, Kwan Mook [1 ]
机构：
[1] Ewha Womans Univ, Dept Chem, Seoul 120750, South Korea
[2] Ewha Womans Univ, Div Nanosci, Seoul 120750, South Korea
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 37期
基金：
新加坡国家研究基金会;
关键词：
chiral ketone; Enantioselective recognition; 1,2-Amino alcohols; imine bond;
D O I：
10.1016/j.tetlet.2007.07.037
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel auxillary chiral ketone has been designed, synthesized, and used to enantioselectively recognize 1,2-amino alcohols. This work proves that the keto group can serve as a chiral recognition center by imine formation supported by resonance assisted hydrogen bonding (RAHB). (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6582 / 6585
页数：4
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