Epigenome-Wide Association Studies Provide Insight into the Pathogenesis of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis

被引：6

作者：

Birerdinc, Aybike ^{[2
]}

Younossi, Zobair M. ^{[1
,2
]}

机构：

[1] Inova Fairfax Hosp, Dept Med & Ctr Liver Dis, Falls Church, VA USA

[2] Inova Hlth Syst, Betty & Guy Beatty Ctr Integrated Res, Falls Church, VA 22042 USA

来源：

ANNALS OF HEPATOLOGY | 2018年 / 17卷 / 01期

关键词：

NASH; NAFLD; EWAS; UNITED-STATES; FERROPTOSIS; EPIDEMIOLOGY; FIBROSIS;

D O I：

10.5604/01.3001.0010.7530

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Non-alcoholic Fatty Liver Disease (NAFLD) and its progressive form or NASH with fibrosis, are rapidly increasing in conjunction with the growing rates of obesity and type II diabetes. Novel technologies such as epigenome-wide association studies (EWAS) may provide opportunities to get valuable insight into not only the mechanisms of disease, but to also discover potential biomarker targets with clinical relevance to disease stage.

引用

页码：11 / 13

页数：3

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