Sleep deprivation alters valuation signals in the ventromedial prefrontal cortex

被引:59
作者
Libedinsky, Camilo [1 ]
Smith, David V. [2 ]
Teng, Chieh Schen [1 ]
Namburi, Praneeth [1 ]
Chen, Vanessa W. [1 ]
Huettel, Scott A. [2 ]
Chee, Michael W. L. [1 ]
机构
[1] Duke NUS, Grad Sch Med, Neurosci & Behav Disorders Program, Singapore 169857, Singapore
[2] Duke Univ, Ctr Cognit Neurosci, Durham, NC USA
来源
FRONTIERS IN BEHAVIORAL NEUROSCIENCE | 2011年 / 5卷
基金
新加坡国家研究基金会;
关键词
sleep deprivation; decision making; reward; valuation; VMPFC; ORBITOFRONTAL CORTEX; NEURAL RESPONSES; ECONOMIC VALUE; ONE NIGHT; BRAIN; REWARD; ANTICIPATION; REPRESENTATION; MONETARY; AMYGDALA;
D O I
10.3389/fnbeh.2011.00070
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Even a single night of total sleep deprivation(SD) can have dramatic effects on economic decision making. Here we tested the novel hypothesis that SD influences economic decisions by altering the valuation process. Using functional magnetic resonance imaging we identified value signals related to the anticipation and the experience of monetary and social rewards (attractive female faces) .We then derived decision value signals that were predictive of each participant's Willingness to exchange money for brief views of attractive faces in an independent market task. Strikingly, SD altered decision value signals inventromedial prefrontal cortex (VMPFC) in proportion to the corresponding change in economic references. These changes in preference were independen to the effects of SD on attention and vigilance. Our results provide novel evidence that signals in VMPFC track the current state of the individual, and thus reflect not static but constructed preferences.
引用
收藏
页数:10
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