Anatomy and Breast Cancer Staging: Is It Still Relevant?

被引:22
作者
Plichta, Jennifer K. [1 ]
Campbell, Brittany M. [1 ]
Mittendorf, Elizabeth A. [2 ]
Hwang, E. Shelley [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Surg, DUMC 3513, Durham, NC 27710 USA
[2] Univ Texas Houston, MD Anderson Canc Ctr, Dept Breast Surg Oncol, 1515 Holcombe Blvd, Houston, TX 77030 USA
关键词
Breast cancer; Staging; Prognosis; Biomarkers; HER-2 NEU ONCOGENE; PROGNOSTIC-FACTOR; HISTOLOGIC GRADE; TUMOR SIZE; SURVIVAL; RECURRENCE; EXPRESSION; DISEASE; AMPLIFICATION; METAANALYSIS;
D O I
10.1016/j.soc.2017.07.010
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Breast cancer staging concisely summarizes disease status, creating a framework for assessing and relaying prognostic information. The fundamental concepts and components of breast cancer staging are reviewed. The AJCC Cancer Staging Manual, which includes traditional anatomic factors, now includes additional tumor characteristics: tumor grade, estrogen receptor status, progesterone receptor status, human epidermal growth factor receptor 2 status, and (when available) multigene panel testing from the primary tumor. With these updates, staging provides the most reliable system for accurately predicting patient outcome. When the AJCC eighth edition guidelines are adopted, they will more closely reflect tumor biology.
引用
收藏
页码:51 / +
页数:18
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