Human Herpesvirus-6 Meningitis in a Premature Infant with Fevers: A Case and Literature Review

被引：10

作者：

Kim, Faith ^{[1
]}

Reichman, Victoria ^{[1
]}

Hooven, Thomas A. ^{[2
]}

机构：

[1] Columbia Univ, Irving Med Ctr, NewYork Presbyterian Morgan Stanley Childrens Hos, Div Neonatol,Dept Pediat, New York, NY USA

[2] UPMC Childrens Hosp Pittsburgh, Div Neonatol Newborn Med, 4401 Penn Ave,Rangos Res Bldg 8128, Pittsburgh, PA 15224 USA

来源：

CLINICAL MEDICINE INSIGHTS-CASE REPORTS | 2020年 / 13卷

关键词：

HHV-6; meningitis; congenital hydrocephalus; prematurity; CENTRAL-NERVOUS-SYSTEM; CHROMOSOMAL INTEGRATION; CLINICAL IMPACT; 6; DNA; INFECTION; HUMAN-HERPESVIRUS-6; TRANSMISSION; CHILDREN; HHV6;

D O I：

10.1177/1179547620912952

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Human herpesvirus-6 (HHV-6) is a common virus that can cause nearly universal infection in infancy and early childhood. It typically manifests as an acute febrile illness. We describe a case of a premature infant with congenital hydrocephalus secondary to aqueductal stenosis with a ventriculoperitoneal shunt in place who developed intermittent fevers while she was admitted to the neonatal intensive care unit. She was ultimately diagnosed with acute HHV-6 meningitis. In addition to this report, we present a literature review regarding this virus's potential modes of transmission and forms of clinical presentation in the neonatal period.

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页数：6

相关论文

共 27 条

[1] Review Part 3: Human Herpesvirus-6 in Multiple Non-Neurological Diseases [J].

Ablashi, Dharam V. ;

Devin, Courtney L. ;

Yoshikawa, Tetsushi ;

Lautenschlager, Irmeli ;

Luppi, Mario ;

Kuehl, Uwe ;

Komaroff, Anthony L. .

JOURNAL OF MEDICAL VIROLOGY, 2010, 82 (11) :1903-1910

[2] Laboratory and Clinical Aspects of Human Herpesvirus 6 Infections [J].

Agut, Henri ;

Bonnafous, Pascale ;

Gautheret-Dejean, Agnes .

CLINICAL MICROBIOLOGY REVIEWS, 2015, 28 (02) :313-335

[3] Viral Detection in Hydrops Fetalis, Spontaneous Abortion, and Unexplained Fetal Death In Utero [J].

Al-Buhtori, Marwan ;

Moore, Lynette ;

Benbow, Emyr W. ;

Cooper, Robert J. .

JOURNAL OF MEDICAL VIROLOGY, 2011, 83 (04) :679-684

[4] HHV-6 INFECTION DURING PREGNANCY AND SPONTANEOUS-ABORTION [J].

ANDO, Y ;

KAKIMOTO, K ;

EKUNI, Y ;

ICHIJO, M .

LANCET, 1992, 340 (8830) :1289-1289

[5] Human herpesviruses 6 and 7 and central nervous system infection in children [J].

Ansari, A ;

Li, SB ;

Abzug, MJ ;

Weinberg, A .

EMERGING INFECTIOUS DISEASES, 2004, 10 (08) :1450-1454

[6] Early Developmental Outcomes of Children With Congenital HHV-6 Infection [J].

Caserta, Mary T. ;

Hall, Caroline B. ;

Canfield, Richard L. ;

Davidson, Philip ;

Lofthus, Gerry ;

Schnabel, Kenneth ;

Carnahan, Jennifer ;

Shelley, Lynne ;

Wang, Hongyue .

PEDIATRICS, 2014, 134 (06) :1111-1118

[7] Possible progesterone-induced gestational activation of chromosomally integrated human herpesvirus 6B and transplacental transmission of activated human herpesvirus 6B [J].

Das, Bibhuti B. ;

Rakheja, Dinesh ;

Lacelle, Chantale ;

Sedlak, Ruth Hall ;

Gulve, Nitish ;

Chowdhury, Suvagata R. ;

Prusty, Bhupesh K. .

JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2016, 35 (11) :1373-1376

[8] Update on human herpesvirus 6 biology, clinical features, and therapy [J].

De Bolle, L ;

Naesens, L ;

De Clercq, E .

CLINICAL MICROBIOLOGY REVIEWS, 2005, 18 (01) :217-+

[9] Evidence of human herpesvirus-6 and-7 reactivation in miscarrying women with pityriasis rosea [J].

Drago, Francesco ;

Broccolo, Francesco ;

Javor, Sanja ;

Drago, Francesca ;

Rebora, Alfredo ;

Parodi, Aurora .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2014, 71 (01) :198-199

[10]

DUNNE WM, 1992, LANCET, V340, P121