CYTOTOXICITY OF COLLOIDAL POLYANILINE DISPERSIONS

被引：0

作者：

Kucekova, Zdenka ^{[1
]}

Humpolicek, Petr ^{[1
]}

Kasparkova, Vera ^{[1
]}

Stejskal, Jaroslav ^{[2
]}

机构：

[1] Tomas Bata Univ Zlin, Zlin, Czech Republic

[2] Acad Sci Czech Republic, Prague, Czech Republic

来源：

NANOCON 2013, 5TH INTERNATIONAL CONFERENCE | 2014年

关键词：

polyaniline; colloidal particles; cytotoxicity; MTT assay; IUPAC TECHNICAL REPORT;

D O I：

暂无

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Cytotoxic effects of colloidal polyaniline dispersions with the particles in the nano-size region (226.5 +/- 5.5 nm) and standard polyaniline powder has been investigated and compared. The mouse embryonic fibroblast cell line (NIH/3T3) was used in the test and the cell viability was detected by MTT assay. The results indicate that concentration of 0.5 % (m/m) of colloidal polyaniline dispersion, corresponding to 90 mu g/mL polyaniline polymer in culture medium is a critical in terms of cell viability. This is higher threshold for cytotoxicity when compared with a standard polyaniline powder, for which the onset of cytotoxicity was observed at concentration of 35 mu g/mL.

引用

页码：687 / 690

页数：4

共 7 条

[1] Biocompatibility of polyaniline [J].