CYTOTOXICITY OF COLLOIDAL POLYANILINE DISPERSIONS

被引:0
作者
Kucekova, Zdenka [1 ]
Humpolicek, Petr [1 ]
Kasparkova, Vera [1 ]
Stejskal, Jaroslav [2 ]
机构
[1] Tomas Bata Univ Zlin, Zlin, Czech Republic
[2] Acad Sci Czech Republic, Prague, Czech Republic
来源
NANOCON 2013, 5TH INTERNATIONAL CONFERENCE | 2014年
关键词
polyaniline; colloidal particles; cytotoxicity; MTT assay; IUPAC TECHNICAL REPORT;
D O I
暂无
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Cytotoxic effects of colloidal polyaniline dispersions with the particles in the nano-size region (226.5 +/- 5.5 nm) and standard polyaniline powder has been investigated and compared. The mouse embryonic fibroblast cell line (NIH/3T3) was used in the test and the cell viability was detected by MTT assay. The results indicate that concentration of 0.5 % (m/m) of colloidal polyaniline dispersion, corresponding to 90 mu g/mL polyaniline polymer in culture medium is a critical in terms of cell viability. This is higher threshold for cytotoxicity when compared with a standard polyaniline powder, for which the onset of cytotoxicity was observed at concentration of 35 mu g/mL.
引用
收藏
页码:687 / 690
页数:4
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