Unilateral subthalamic nucleus deep brain stimulation contralateral to thalamic stimulation in Parkinson disease

被引：1

作者：

Samii, A

Slimp, JC

Goodkin, R

机构：

[1] Univ Washington, Sch Med, Dept Neurol, VAPSHCS, Seattle, WA 98108 USA

[2] Univ Washington, Sch Med, Dept Rehabil Med, Seattle, WA 98195 USA

[3] Univ Washington, Sch Med, Dept Neurol Surg, Seattle, WA 98195 USA

来源：

PARKINSONISM & RELATED DISORDERS | 2005年 / 11卷 / 04期

关键词：

Parkinson disease; deep brain stimulation; thalamus; subthalamic nucleus; tremor;

D O I：

10.1016/j.parkreldis.2004.10.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The effects of unilateral subthalamic nucleus (STN) stimulation contralateral to thalamic stimulation in Parkinson disease (PD) have not been previously reported. We are reporting a patient who developed left arm tremor in 1994, at age 62, as her first PD symptom. She underwent right thalamic DBS surgery in 1999 that resulted in complete resolution of left arm tremor. Her PD symptoms progressed and she developed severe motor fluctuations and disabling dyskinesias. In 2003, she underwent left STN electrode implantation. Left STN stimulation improved contralateral motor scores in the medication OFF state,,and allowed for reduced medication doses and less dyskinesia. However, there was no significant improvement in activities of daily living (ADL), motor scores in the medication ON state, gait, or postural stability. © 2004 Elsevier Ltd. All rights reserved.

引用

页码：257 / 258

页数：2

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