Faster multiple emulsification with drop splitting

被引:122
作者
Abate, Adam R. [1 ]
Weitz, David A. [1 ]
机构
[1] Harvard Univ, Sch Engn & Appl Sci, Dept Phys, Cambridge, MA 02138 USA
基金
美国国家科学基金会;
关键词
MONODISPERSE DOUBLE EMULSIONS; BUBBLES;
D O I
10.1039/c0lc00706d
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Microfluidic devices can form emulsions in which the drops have an intricate, controlled structure; however, a challenge is that the droplets are produced slowly, typically only a few millilitres per hour. Here, we present a simple technique to increase the production rate. Using a large drop maker, we produce large drops at a fast volumetric rate; by splitting these drops several times in a splitting array, we create drops of the desired small size. The advantage of this over forming the small drops directly using a small drop maker is that the drops can be formed at much faster rates. This can be applied to the production of single and multiple emulsions.
引用
收藏
页码:1911 / 1915
页数:5
相关论文
共 27 条
  • [1] High-Order Multiple Emulsions Formed in Poly(dimethylsiloxane) Microfluidics
    Abate, A. R.
    Weitz, D. A.
    [J]. SMALL, 2009, 5 (18) : 2030 - 2032
  • [2] Abate AR, 2011, LAB CHIP, V11, P253, DOI [10.1039/c0lc00236d, 10.1039/c01c00236d]
  • [3] Patterning microfluidic device wettability using flow confinement
    Abate, Adam R.
    Thiele, Julian
    Weinhart, Marie
    Weitz, David A.
    [J]. LAB ON A CHIP, 2010, 10 (14) : 1774 - 1776
  • [4] Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability
    Abate, Adam R.
    Krummel, Amber T.
    Lee, Daeyeon
    Marquez, Manuel
    Holtze, Christian
    Weitz, David A.
    [J]. LAB ON A CHIP, 2008, 8 (12) : 2157 - 2160
  • [5] Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions
    Bauer, Wolfgang-Andreas C.
    Fischlechner, Martin
    Abell, Chris
    Huck, Wilhelm T. S.
    [J]. LAB ON A CHIP, 2010, 10 (14) : 1814 - 1819
  • [6] THE MOTION OF LONG BUBBLES IN TUBES
    BRETHERTON, FP
    [J]. JOURNAL OF FLUID MECHANICS, 1961, 10 (02) : 166 - 188
  • [7] Controllable monodisperse multiple emulsions
    Chu, Liang-Yin
    Utada, Andrew S.
    Shah, Rhutesh K.
    Kim, Jin-Woong
    Weitz, David A.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (47) : 8970 - 8974
  • [8] Capillary threads and viscous droplets in square microchannels
    Cubaud, Thomas
    Mason, Thomas G.
    [J]. PHYSICS OF FLUIDS, 2008, 20 (05)
  • [9] Edris A, 2001, NAHRUNG, V45, P133, DOI 10.1002/1521-3803(20010401)45:2<133::AID-FOOD133>3.0.CO
  • [10] 2-C