Selective cytotoxic activities of leaf essential oils from Monteverde, Costa Rica

被引：0

作者：

Moriarity, Debra M. ^{[1
]}

Bansala, Anita ^{[1
]}

Cole, Ramona A. ^{[2
]}

Takaku, Sayaka ^{[2
]}

Haber, William A. ^{[3
]}

Setzer, William N. ^{[2
]}

机构：

[1] Univ Alabama, Dept Biol Sci, Huntsville, AL 35899 USA

[2] Univ Alabama, Dept Chem, Huntsville, AL 35899 USA

[3] Missouri Bot Garden, St Louis, MO 63166 USA

来源：

NATURAL PRODUCT COMMUNICATIONS | 2007年 / 2卷 / 12期

关键词：

Eugenia; Myrcia; Ocotea; Persea; essential oils; chemical composition; cytotoxicity;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The leaf essential oils of Eugenia cartagensis, Myrcia sp. nov. "fuzzy leaf", Ocotea veraguensis, O. whitei, and Persea americana, have been obtained by hydrodistillation and the essential oil compositions determined by GC-MS. The essential oils have been screened for in-vitro cytotoxic activity against a panel of human tumor cell lines, and each of the species shows selective cytotoxic activity. E. cartagensis was active against HCT-15 and SW 620 human colorectal carcinoma cells, O. veraguensis and Myrcia "fuzzy leaf" were cytotoxic to MDA-MB-231 and MDA-MB-468 mammary adenocarcinoma cells, and O. whitei and Persea americana were toxic to M-14 melanoma cells.

引用

页码：1263 / 1268

页数：6

共 23 条

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