Biochemistry of oxidative stress

被引:1060
作者
Halliwell, B. [1 ]
机构
[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem, Singapore 117597, Singapore
关键词
antioxidant; cancer; cell culture; oxidative damage; oxidative stress; senescence;
D O I
10.1042/BST0351147
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The terms 'antioxidant', 'oxidative stress' and 'oxidative damage' are widely used but rarely defined. This brief review attempts to define them and to examine the ways in which oxidative stress and oxidative damage can affect cell behaviour both in vivo and in cell culture, using cancer as an example.
引用
收藏
页码:1147 / 1150
页数:4
相关论文
共 49 条
[1]   Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra [J].
Alam, ZI ;
Jenner, A ;
Daniel, SE ;
Lees, AJ ;
Cairns, N ;
Marsden, CD ;
Jenner, P ;
Halliwell, B .
JOURNAL OF NEUROCHEMISTRY, 1997, 69 (03) :1196-1203
[2]   OXIDANT-INDUCED ALTERATIONS IN GLUCOSE AND PHOSPHATE-TRANSPORT IN LLC-PK1 CELLS - MECHANISMS OF INJURY [J].
ANDREOLI, SP ;
MCATEER, JA ;
SEIFERT, SA ;
KEMPSON, SA .
AMERICAN JOURNAL OF PHYSIOLOGY, 1993, 265 (03) :F377-F384
[3]   When cells get stressed: an integrative view of cellular senescence [J].
Ben-Porath, I ;
Weinberg, RA .
JOURNAL OF CLINICAL INVESTIGATION, 2004, 113 (01) :8-13
[4]   OXIDATIVE STRESS AND TUMOR-CELL PROLIFERATION [J].
BURDON, RH ;
GILL, V ;
RICEEVANS, C .
FREE RADICAL RESEARCH COMMUNICATIONS, 1990, 11 (1-3) :65-76
[5]   HYDROGEN-PEROXIDE AND THE PROLIFERATION OF BHK-21-CELLS [J].
BURDON, RH ;
ALLIANGANA, D ;
GILL, V .
FREE RADICAL RESEARCH, 1995, 23 (05) :471-486
[6]   Physiology - A welcome shortage of breath [J].
Burmester, T .
NATURE, 2005, 433 (7025) :471-472
[7]  
Cabiscol E, 2000, J BIOL CHEM, V275, P27393
[8]   HYDROGEN-PEROXIDE AND SUPEROXIDE RADICAL FORMATION IN ANAEROBIC BROTH MEDIA EXPOSED TO ATMOSPHERIC OXYGEN [J].
CARLSSON, J ;
NYBERG, G ;
WERTHEN, J .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1978, 36 (02) :223-229
[9]   Contribution of hydrogen peroxide to the cytotoxicity of green tea and red wines [J].
Chai, PC ;
Long, LH ;
Halliwell, B .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 304 (04) :650-654
[10]   Redox regulation of PTEN and protein tyrosine phosphatases in H2O2-mediated cell signaling [J].
Cho, SH ;
Lee, CH ;
Ahn, Y ;
Kim, H ;
Kim, H ;
Ahn, CY ;
Yang, KS ;
Lee, SR .
FEBS LETTERS, 2004, 560 (1-3) :7-13