Current Status of Antiplatelet Agents to Prevent Stroke

被引：11

作者：

Field, Thalia S. ^{[1
]}

Benavente, Oscar R. ^{[1
]}

机构：

[1] Univ British Columbia, Dept Med, Div Neurol, Brain Res Ctr, Vancouver, BC V6T 2B5, Canada

来源：

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS | 2011年 / 11卷 / 01期

关键词：

Stroke; TIA; Antiplatelet; Prevention; Aspirin; Clopidogrel; Dipyridamole; Warfarin; Trial; Aspirin failure; Clopidogrel resistance; Cardioembolic; TRANSIENT ISCHEMIC ATTACK; PERCUTANEOUS CORONARY INTERVENTION; ASPIRIN RESISTANCE; SECONDARY PREVENTION; INTRACEREBRAL HEMORRHAGE; CEREBRAL MICROBLEEDS; DOUBLE-BLIND; RISK-FACTOR; CLOPIDOGREL; THERAPY;

D O I：

10.1007/s11910-010-0162-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Stroke is one of the leading causes of disability; most are due to atherothrombotic mechanisms. About one third of ischemic strokes are preceded by other stroke or transient ischemic attacks. Stroke survivors are at high risk for vascular events (i.e., cerebrovascular and cardiovascular). Prevention of recurrent stroke and other major vascular events can be accomplished by control of risk factors. Nonetheless, the use of antiplatelet agents remains the fundamental component of secondary stroke prevention strategy in patients with noncardioembolic disease. Currently, the uses of aspirin, clopidogrel, or aspirin plus extended-release dipyridamole are valid alternatives for stroke or transient ischemic attack patients. To maximize the beneficial effects of these agents, the treatment should be initiated as early as possible and continue on a lifelong basis.

引用

页码：6 / 14

页数：9

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