Presentation of acute promyelocytic leukemia as granulocytic sarcoma

被引：26

作者：

Worch, Jennifer ^{[1
]}

Ritter, Joerg ^{[1
]}

Fruehwald, Michael C. ^{[1
]}

机构：

[1] Univ Childrens Hosp Muenster, Dept Pediat Hematol & Oncol, D-48129 Munster, Germany

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 50卷 / 03期

关键词：

acute promyelocytic leukemia (APL); extramedullary leukemia; granulocytic sarcoma (GS);

D O I：

10.1002/pbc.21190

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Granulocytic sarcoma (GS) is I localized tumor composed of immature myeloid cells. This extramedullary tumor can present before, concurrent with or after the diagnosis of acute myeloid leukemia. GS is extremely uncommon in acute promyelocytic leukemia (APL). As a proportion of patients never-develop systemic disease, correct and timely diagnosis may be rather difficult, but is a prerequisite for optimal outcome. GS should be considered in the differential diagnosis of children with unusual bone lesions. We describe a patient with GS who presented with symptoms mimicking osteomyelytis or rheumatoid disease.

引用

页码：657 / 660

页数：4

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