IL-7Rα and multiple sclerosis risk

被引：9

作者：

Harley, John B.

机构：

[1] Oklahoma Med Res Fdn, Arthrit & Immunol Program, Oklahoma City, OK 73104 USA

[2] US Dept Vet Affairs, Med Ctr, Oklahoma City, OK 73104 USA

来源：

NATURE GENETICS | 2007年 / 39卷 / 09期

关键词：

D O I：

10.1038/ng0907-1053

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The discovery of genetic risk factors for multiple sclerosis has proven difficult. IL- 7R alpha, encoded by IL7R, is a pleiomorphic cytokine receptor now implicated in the pathogenesis of multiple sclerosis in independently replicated genetic association studies.

引用

页码：1053 / 1054

页数：2