N-HeterocyclicCarbene Organocatalysis: Activation Modes and Typical Reactive Intermediates

被引：230

作者：

Chen, Xingkuan ^{[1
]}

Wang, Hongling ^{[2
]}

Jin, Zhichao ^{[2
]}

Chi, Yonggui Robin ^{[2
,3
]}

机构：

[1] Jinan Univ, Dept Chem, Guangzhou 510632, Guangdong, Peoples R China

[2] Guizhou Univ, Lab Breeding Base Green Pesticide & Agr Bioengn, Key Lab Green Pesticide & Agr Bioengn, Minist Educ, Guiyang 550025, Guizhou, Peoples R China

[3] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

CHINESE JOURNAL OF CHEMISTRY | 2020年 / 38卷 / 10期

基金：

中国国家自然科学基金;

关键词：

N-Heterocyclic carbene; Organocatalysis; Activation mode; Reactive intermediates; Homogeneous catalysis; HIGHLY ENANTIOSELECTIVE SYNTHESIS; INTERMOLECULAR STETTER REACTION; DYNAMIC KINETIC RESOLUTION; CARBENE-CATALYZED GENERATION; SATURATED CARBOXYLIC ESTERS; ISATIN-DERIVED KETIMINES; DIELS-ALDER REACTIONS; AZA-BENZOIN REACTION; ALPHA; BETA-UNSATURATED ACYL CHLORIDES; BICYCLIC DELTA-LACTONES;

D O I：

10.1002/cjoc.202000107

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Heterocyclic carbene (NHC) organocatalysis has been developed as an important approach in modern organic synthesis. Versatile activation modes within NHC organocatalysis have been established with countless transformations being realized in both efficient and selective fashion. We would like to provide an overview on the key progresses achieved within this field in the past two decades. Since numerous excellent reviews have been documented within this area, we will mainly focus on the scientific development of this research field based on the basic reaction modes and typical reaction intermediates.

引用

页码：1167 / 1202

页数：36

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