18FDG-PET/CT in staging and measuring the efficacy of neoadjuvant chemotherapy in breast cancer

被引:1
作者
Groheux, D. [1 ,2 ]
Hindie, E. [3 ,4 ]
机构
[1] Hop St Louis, Nucl Med Serv, F-75475 Paris 10, France
[2] Ctr Imagerie Radioisotop, F-17000 La Rochelle, France
[3] CHU Bordeaux, Hop Haut Leveque, Nucl Med Serv, F-33000 Bordeaux, France
[4] Univ Bordeaux, F-33000 Bordeaux, France
来源
MEDECINE NUCLEAIRE-IMAGERIE FONCTIONNELLE ET METABOLIQUE | 2015年 / 39卷 / 03期
关键词
(18)FDG; PET/CT; Breast cancer; Staging; Prognosis; Neoadjuvant treatment; Response assessment; Pathological complete response; Triple-negative breast cancer; HER2-positive breast cancer; ER-positive breast cancer; POSITRON-EMISSION-TOMOGRAPHY; PATHOLOGICAL COMPLETE RESPONSE; EARLY METABOLIC-RESPONSE; LONG-TERM SURVIVAL; F-18-FDG PET/CT; FDG-PET/CT; EARLY PREDICTION; OPEN-LABEL; PREOPERATIVE CHEMOTHERAPY; BLOOD-FLOW;
D O I
10.1016/j.mednuc.2015.03.003
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Accurate staging is of importance for taking appropriate management decisions in a patient with newly diagnosed breast cancer. The role of (18)FDG-imaging in detecting extra-axillary lymph node involvement and distant lesions in high-risk breast cancer patients is highlighted. This review also discusses potential roles of (18)FDG-PET/CT in early assessing response to neoadjuvant chemotherapy. Interim-PET/CT received increased attention in recent years through pilot studies exploring its role in specific subtypes of breast cancer. Results of a French trial that used early metabolic response with (18)FDG-PET/CT as a means to select poor responders for intensification have been recently published, with encouraging results. (C) 2015 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:315 / 326
页数:12
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