CHOLINESTERASE INHIBITORS AND MEMANTINE FOR THE TREATMENT OF ALZHEIMER AND NON-ALZHEIMER DEMENTIAS

被引:22
|
作者
Balazs, Nora [1 ]
Bereczki, Daniel [1 ,2 ]
Kovacs, Tibor [1 ,2 ]
机构
[1] Semmelweis Univ, Dept Neurol, Balassa U 6, H-1083 Budapest, Hungary
[2] MTA SE Neuroepidemiol Res Grp ELKH, Budapest, Hungary
来源
IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE | 2021年 / 74卷 / 11-12期
关键词
dementia; therapy; treatment; cholinesterase inhibitors; memantine; ACETYLCHOLINESTERASE INHIBITORS; ANTIDEMENTIA DRUGS; DISEASE; ASSOCIATION; DIAGNOSIS; MODERATE; RIVASTIGMINE; MANAGEMENT; ATROPHY;
D O I
10.18071/isz.74.0379
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In aging societies, the morbidity and mortality of dementia is increasing at a significant rate, thereby imposing burden on healthcare, economy and the society as well. Patients' and caregivers' quality of life and life expectancy are greatly determined by the early diagnosis and the initiation of available symptomatic treatments. Cholinesterase inhibitors and memantine have been the cornerstones of Alzheimer's therapy for approximately two decades and over the years, more and more experience has been gained on their use in non-Alzheimer's dementias too. The aim of our work was to provide a comprehensive summary about the use of cholinesterase inhibitors and memantine for the treatment of Alzheimer's and non-Alzheimers's dementias.
引用
收藏
页码:379 / 387
页数:9
相关论文
共 50 条
  • [21] Cholinesterase Inhibitors: Cardioprotection in Alzheimer's Disease
    Monacelli, Fiammetta
    Rosa, Gianmarco
    JOURNAL OF ALZHEIMERS DISEASE, 2014, 42 (04) : 1071 - 1077
  • [22] Comparative safety and effectiveness of cholinesterase inhibitors and memantine for Alzheimer's disease: a network meta-analysis of 41 randomized controlled trials
    Dou, Kai-Xin
    Tan, Meng-Shan
    Tan, Chen-Chen
    Cao, Xi-Peng
    Hou, Xiao-He
    Guo, Qi-Hao
    Tan, Lan
    Mok, Vincent
    Yu, Jin-Tai
    ALZHEIMERS RESEARCH & THERAPY, 2018, 10
  • [23] Defining optimal treatment with cholinesterase inhibitors in Alzheimer's disease
    Small, Gary
    Bullock, Roger
    ALZHEIMERS & DEMENTIA, 2011, 7 (02) : 177 - 184
  • [24] Cholinesterase inhibitors as Alzheimer's therapeutics
    Sharma, Kamlesh
    MOLECULAR MEDICINE REPORTS, 2019, 20 (02) : 1479 - 1487
  • [25] Non-Alzheimer's disease dementias: Anatomic, clinical, and molecular correlates
    Hou, CE
    Carlin, D
    Miller, BL
    CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2004, 49 (03): : 164 - 171
  • [26] Test Your Memory (TYM test): diagnostic evaluation of patients with non-Alzheimer dementias
    Brown, Jeremy
    Wiggins, Julie
    Lansdall, Claire J.
    Dawson, Kate
    Rittman, Timothy
    Rowe, James B.
    JOURNAL OF NEUROLOGY, 2019, 266 (10) : 2546 - 2553
  • [27] Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias
    Kaivola, Karri
    Chia, Ruth
    Ding, Jinhui
    Rasheed, Memoona
    Fujita, Masashi
    Menon, Vilas
    Walton, Ronald L.
    Collins, Ryan L.
    Billingsley, Kimberley
    Brand, Harrison
    Talkowski, Michael
    Zhao, Xuefang
    Dewan, Ramita
    Stark, Ali
    Ray, Anindita
    Solaiman, Sultana
    Jerez, Pilar Alvarez
    Malik, Laksh
    Dawson, Ted M.
    Rosenthal, Liana S.
    Albert, Marilyn S.
    Pletnikova, Olga
    Troncoso, Juan C.
    Maselis, Mario
    Keith, Julia
    Black, Sandra E.
    Ferrucci, Luigi
    Resnick, Susan M.
    Tanaka, Toshiko
    Topol, Eric
    Torkamani, Ali
    Tienari, Pentti
    Foroud, Tatiana M.
    Ghetti, Bernardino
    Landers, John E.
    Rtyen, Mina
    Morris, Huw R.
    Hardy, John A.
    Mazzini, Letizia
    D'Alfonso, Sandra
    Moglia, Cristina
    Calvo, Andrea
    Serrano, Geidy E.
    Beach, Thomas G.
    Ferman, Tanis
    Graff-Radford, Neill R.
    Boeve, Bradley F.
    Wszolek, Zbigniew K.
    Dickson, Dennis W.
    Chio, Adriano
    CELL GENOMICS, 2023, 3 (06):
  • [28] EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease
    Schmidt, R.
    Hofer, E.
    Bouwman, F. H.
    Buerger, K.
    Cordonnier, C.
    Fladby, T.
    Galimberti, D.
    Georges, J.
    Heneka, M. T.
    Hort, J.
    Laczo, J.
    Molinuevo, J. L.
    O'Brien, J. T.
    Religa, D.
    Scheltens, P.
    Schott, J. M.
    Sorbi, S.
    EUROPEAN JOURNAL OF NEUROLOGY, 2015, 22 (06) : 889 - 898
  • [29] Detection of Alzheimer Neuropathology in Alzheimer and Non-Alzheimer Clinical Syndromes With Blood-Based Biomarkers
    Vandevrede, Lawren
    Cho, Hanna
    Sanderson-Cimino, Mark
    Wekselman, Fattin
    Cobigo, Yann
    Gorno-Tempini, Maria Luisa
    Heuer, Hilary W.
    Kramer, Joel H.
    Lario Lago, Argentina
    Leichter, Dana
    Ljubenkov, Peter
    Miller, Bruce L.
    Perry, David C.
    Rabinovici, Gil D.
    Rojas, Julio C.
    Rosen, Howard J.
    Saloner, Rowan
    Staffaroni, Adam
    Triana-Baltzer, Gallen
    Spina, Salvatore
    Seeley, William W.
    Grinberg, Lea T.
    Kolb, Hartmuth C.
    La Joie, Renaud
    Boxer, Adam L.
    JAMA NEUROLOGY, 2025,
  • [30] Cost-utility analysis of memantine extended release added to cholinesterase inhibitors compared to cholinesterase inhibitor monotherapy for the treatment of moderate-to-severe dementia of the Alzheimer's type in the US
    Thibault, Catherine Saint-Laurent
    Stillman, Ipek Oezer
    Chen, Stephanie
    Getsios, Denis
    Proskorovsky, Irina
    Hernandez, Luis
    Dixit, Shailja
    JOURNAL OF MEDICAL ECONOMICS, 2015, 18 (11) : 930 - 943