Reaction of different functional zones in mouse thymus and spleen lymphoid tissue to γ-irradiation

被引：1

作者：

Sapin, MP ^{[1
]}

Erofeeva, LM ^{[1
]}

Grigorenko, DE ^{[1
]}

Fedorenko, BS ^{[1
]}

机构：

[1] Russian Acad Med Sci, Inst Human Morphol, Funct Anat Lab, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1998年 / 125卷 / 04期

关键词：

thymus; spleen; lymphocyte; gamma-irradiation;

D O I：

10.1007/BF02499175

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

It is shown that immune organs respond to single gamma-radiation of 6.9 Gy in a cyclic manner.. Acute reaction characterized by spontaneous lymphocyte lysis in the thymus and spleen develops on day I postirradiation sind takes 3 and 7 days, respectively. This is followed by enhancement of thymocyte mitotic activity and migration of young cells to the thymic cortex and splenic lymphoid tissue. Twenty-one day postirradiation lymphoid cell populations in the thymus and spleen recover to 70-90 and 55-70%, respectively.

引用

页码：416 / 419

页数：4

共 5 条

[1] EFFECT OF PHYSICAL LOADS OF DIFFERENT INTENSITY ON ELEMENTS OF THE LYMPHOID-TISSUE OF THE THYMUS AND SPLEEN
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[5] Morphological and Functional Changes in the Thymus and Spleen of Mouse Offspring in the Development of Systemic Inflammatory Response After a Single Immunity Stimulation in Early Pregnancy
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