A regioselective synthesis of methyl 7-amino-3-phenylthieno-[2,3-b]pyrazine-6-carboxylate

被引：3

作者：

Zhang, WJ ^{[1
]}

Haight, AR ^{[1
]}

Ford, KL ^{[1
]}

Parekh, SI ^{[1
]}

机构：

[1] Abbott Labs, Chem Proc Res, N Chicago, IL 60064 USA

来源：

SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 05期

关键词：

D O I：

10.1081/SCC-100103262

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practical synthesis of methyl 7-amino-3-phenylthieno[2,3-b]pyrazine-6-carboxylate (1) has been achieved via a regioselective synthesis of 3-cyano-5-phenyl-3-phenylthiopyrazine (5a), by condensing 1,1 -diethoxyacetophenone with 2,3-diamino-3-phenylthioacrylonitrile.

引用

页码：725 / 730

页数：6

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