A regioselective synthesis of methyl 7-amino-3-phenylthieno-[2,3-b]pyrazine-6-carboxylate

被引：3
|
作者：
Zhang, WJ [1 ]
Haight, AR [1 ]
Ford, KL [1 ]
Parekh, SI [1 ]
机构：
[1] Abbott Labs, Chem Proc Res, N Chicago, IL 60064 USA
来源：
SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 05期
关键词：
D O I：
10.1081/SCC-100103262
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A practical synthesis of methyl 7-amino-3-phenylthieno[2,3-b]pyrazine-6-carboxylate (1) has been achieved via a regioselective synthesis of 3-cyano-5-phenyl-3-phenylthiopyrazine (5a), by condensing 1,1 -diethoxyacetophenone with 2,3-diamino-3-phenylthioacrylonitrile.
引用
收藏
页码：725 / 730
页数：6
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