Lymphoproliferative responses in pigs infected with Mycobacterium avium

被引:5
|
作者
Iwakiri, A [1 ]
Toshimasu, M [1 ]
Xu, DL [1 ]
Shinjo, T [1 ]
Goto, Y [1 ]
机构
[1] Miyazaki Univ, Fac Agr, Dept Vet Microbiol, Miyazaki 8892192, Japan
来源
JOURNAL OF VETERINARY MEDICAL SCIENCE | 2001年 / 63卷 / 07期
关键词
lymphoproliferative response (LPR); Mycobacterium avium; swine;
D O I
10.1292/jvms.63.827
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Naturally infected cases of swine mycobacteriosis were divided into two groups, localized infection (LI) and disseminated infection (DI). Lymphoproliferative response (LPR) was then examined to estimate their immunological states. Both control and LI groups showed strong response to Concanavalin A (Con A) and phytohemagglutinin (PHA) in the LPR, and lymphocytes recovered from the LI responded well to purified protein derived from M. avium (PPD). On the other hand, the DI group showed weak response to both Con A and PHA, despite their strong response to PPD stimulation. These data suggest that the low LPR to Con A and PHA observed in the DI groups was probably not due to the general unresponsiveness of T-cells.
引用
收藏
页码:827 / 829
页数:3
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