Electrochemical Determination of L-Dopa in Mucuna pruriens Seeds, Leaves and Commercial Siddha Product Using Gold Modified Pencil Graphite Electrode

被引：26

作者：

Kalachar, H. C. B. ^{[1
]}

Basavanna, S. ^{[2
]}

Viswanatha, R. ^{[1
]}

Naik, Y. Arthoba ^{[1
]}

Raj, D. Ananda ^{[3
]}

Sudhad, P. N. ^{[4
]}

机构：

[1] Kuvempu Univ, Sch Chem Sci, Dept Chem, Shankaraghatta 577451, India

[2] Indian Inst Sci, Solid State & Struct Chem Unit, Bangalore 560012, Karnataka, India

[3] SCSVMV Univ, Dept Chem, Enathur 631561, Kanchipuram, India

[4] DKM Coll Women, Vellore 632001, Tamil Nadu, India

来源：

ELECTROANALYSIS | 2011年 / 23卷 / 05期

关键词：

Ascorbic acid; Cyclic voltammetry; Differential pulse voltammetry; L-Dopa; Mucuna pruriens; VOLTAMMETRIC DETERMINATION; NANOPARTICLES; OXIDATION; (L)-DOPA; BEHAVIOR; SENSOR; HP-200; FILM; RAW;

D O I：

10.1002/elan.201000558

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In the present work a gold modified pencil graphite electrode (GPGE) was used for the determination of L-dopa present in the aqueous extracts of Mucuna pruriens seeds (MPS), Mucuna pruriens leaves (MPL) and Commercial Siddha Product (CSP). The GPGE shows excellent electrocatalytic activity towards the oxidation of both L-dopa and ascorbic acid (AA), with the separation of peak potential of 98 mV. The differential pulse voltammetric (DPV) results indicated that the detection limit for L-dopa was 1.54 mu M (S/N=3). This method can be successfully applied for the determination of L-dopa in real samples.

引用

页码：1107 / 1115

页数：9

共 36 条

[1] [Anonymous], CHEM REV
[2] A disposaable electrochemical sensor for the rapid determination of levodopa
Bergamini, MF
Santos, AL
Stradiotto, NR
Zanoni, MVB
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2005, 39 (1-2) : 54 - 59
[3] Composition and functional properties of raw and electron beam-irradiated Mucuna pruriens seeds
Bhat, Rajeev
Sridhar, Kandikere R.
Young, Chiu-Chung
Bhagwath, Arun A.
Ganesh, Sanjeev
[J]. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2008, 43 (08) : 1338 - 1351
[4] Gold nanoparticles: Assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology
Daniel, MC
Astruc, D
[J]. CHEMICAL REVIEWS, 2004, 104 (01) : 293 - 346
[5] Simultaneous differential pulse voltammetric determination of l-dopa and Carbidopa in pharmaceuticals using a carbon paste electrode modified with lead dioxide immobilized in a polyester resin
de Melo, Helio Correa
Seleghim, Ana Paula D.
Polito, Wagner Luiz
Fatibello-Filho, Orlando
Vieira, Iolanda C.
[J]. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2007, 18 (04) : 797 - 803
[6] Dean J. A., 1973, LANGE S HDB CHEM
[7] Fujii Yoshiharu, 2003, Biol Sci Space, V17, P6, DOI 10.2187/bss.17.6
[8] Sensitive detection of haloperidol and hydroxyzine at multi-walled carbon nanotubes-modified glassy carbon electrodes
Huang, Fei
Peng, Youyuan
Jin, Guiying
Zhang, Song
Kong, Jilie
[J]. SENSORS, 2008, 8 (03) : 1879 - 1889
[9] Synthesis of flower-like gold nanoparticles and their electrocatalytic activity towards the oxidation of methanol and the reduction of oxygen
Jena, Bikash Kumar
Raj, C. Retna
[J]. LANGMUIR, 2007, 23 (07) : 4064 - 4070
[10] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF DOPACHROME AND DIHYDROXYPHENYLALANINE
KAGEDAL, B
KONRADSSON, P
SHIBATA, T
MISHIMA, Y
[J]. ANALYTICAL BIOCHEMISTRY, 1995, 225 (02) : 264 - 269

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