Application of polymer-supported triphenylphosphine and microwave irradiation to the palladium-catalyzed cyanation of aryl triflates

被引：19

作者：

Srivastava, Rajiv R. ^{[1
]}

Zych, Andrew J. ^{[1
]}

Jenkins, David M. ^{[1
]}

Wang, Hong-Jun ^{[1
]}

Chen, Zhen-Jia ^{[1
]}

Fairfax, David J. ^{[1
]}

机构：

[1] Albany Mol Res Inc, Dept Med Chem, Albany, NY 12212 USA

来源：

SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 1-3期

关键词：

aryl triflates; heterogeneous catalyst; microwave irradiation; nitriles; palladium; thermal heating;

D O I：

10.1080/00397910601039044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of aryl nitriles were prepared in excellent yield from the palladium(II) acetate-catalyzed cross-coupling of aryl triflates and zinc cyanide under microwave irradiation conditions. To facilitate purification, polymer-supported triphenylphosphine was used as the palladium ligand. Comparison to the corresponding thermal conditions revealed much shorter reaction times with comparable yields.

引用

页码：431 / 438

页数：8

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