Family-based association study of microsatellites in the 5′ flanking region of AVPR1A with autism spectrum disorder in the Korean population

被引：28

作者：

Yang, So Young ^{[1
]}

Cho, Soo-Churl ^{[2
]}

Yoo, Hee Jeong ^{[3
]}

Cho, In Hee ^{[4
]}

Park, Mira ^{[5
]}

Yoe, Jin ^{[1
]}

Kim, Soon Ae ^{[1
,6
]}

机构：

[1] Eulji Univ, Dept Pharmacol, Sch Med, Taejon 301746, South Korea

[2] Seoul Natl Univ, Coll Med, Dept Psychiat, Seoul Natl Univ Hosp, Seoul, South Korea

[3] Seoul Natl Univ, Bundang Hosp, Dept Psychiat, Songnam, Kyeonggi, South Korea

[4] Gachon Univ Med & Sci, Dept Psychiat, Gil Med Ctr, Inchon, South Korea

[5] Eulji Univ, Dept Prevent Med, Sch Med, Taejon 301746, South Korea

[6] Eulji Univ, Med Sci Res Inst, Taejon 301746, South Korea

来源：

PSYCHIATRY RESEARCH | 2010年 / 178卷 / 01期

关键词：

Autism spectrum disorder (ASD); AVPR1A; Association; VASOPRESSIN; BEHAVIOR; GENE;

D O I：

10.1016/j.psychres.2009.11.007

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This study evaluated the association between autism spectrum disorders (ASDs) and microsatellites (RS3 and RS1) in the 5' flanking region of AVPR1A in 148 Korean trios comprising children with ASDs. In the transmission equilibrium test and haplotype analysis, we found a statistically significant association between microsatellites and Korean ASDs. Crown Copyright (C) 2009 Published by Elsevier Ireland Ltd. All rights reserved.

引用

页码：199 / 201

页数：3

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