Renal Evaluation and Protection

被引:5
作者
Amir, Rawan [1 ]
Suhl, Sara [2 ]
Alexander, Charles M. [3 ]
机构
[1] Cent Michigan Univ, Coll Med, Dept Med, 1000 Houghton Ave, Saginaw, MI 48602 USA
[2] dQ&A Diabet Res, 804 Haight St, San Francisco, CA 94117 USA
[3] Alexander Associates LLC, POB 351, Gwynedd Valley, PA 19437 USA
关键词
Diabetic nephropathy; Type; 2; diabetes; Albuminuria; Chronic kidney disease; CARDIOVASCULAR OUTCOMES; DIABETIC-NEPHROPATHY; KIDNEY-DISEASE; MORTALITY; RISK; LIRAGLUTIDE; MANAGEMENT;
D O I
10.1016/j.cger.2020.04.004
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Diabetes and diabetic nephropathy have become more prevalent in the elderly population. Diabetic nephropathy has become increasingly prevalent in the elderly population. The presence of this disease in an age group suffering multiple comorbidities has altered the pathophysiology and leading cause of mortality. Mortality has become linked more often to cardiovascular events rather than progression of end-stage-renaldisease, which explains the recent shift of focus of trials to improving cardiovascular-outcomes in patients with diabetes. In this chapter, we emphasize the difference in treatment modalities and goals of therapy in elderly versus young. In addition, we discuss results from recent outcome trials with regards to renal benefits of sodium-glucose co-transporter-2-inhibitors and glucagon-like peptide-1-receptoragonists.
引用
收藏
页码:431 / +
页数:16
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