Is There a Future for Endovascular Treatment of Intracranial Atherosclerotic Disease After Stenting and Aggressive Medical Management for Preventing Recurrent Stroke and Intracranial Stenosis (SAMMPRIS)?

被引：28
作者：
Marks, Michael P. [1 ,2 ]
机构：
[1] Stanford Univ, Med Ctr, Dept Radiol, Stanford, CA 94305 USA
[2] Stanford Univ, Med Ctr, Dept Neurosurg, Stanford, CA 94305 USA
来源：
STROKE | 2012年 / 43卷 / 02期
关键词：
angioplasty & stenting; atherosclerosis; stents; DRUG-ELUTING STENT; TERM-FOLLOW-UP; WINGSPAN STENT; ANGIOPLASTY; EXPERIENCE; PLACEMENT; PREDICTORS; RESTENOSIS; OUTCOMES; REGISTRY;
D O I：
10.1161/STROKEAHA.111.645507
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke and Intracranial Stenosis (SAMMPRIS) trial, a randomized clinical trial comparing aggressive medical management to stenting with aggressive medical management for symptomatic intracranial stenosis, was prematurely halted when a high rate of periprocedural events was found in the stent arm. The trial also demonstrated a high rate of stroke with medical management. This article explores possible reasons for these outcomes and discusses some weaknesses of the trial. Against this background endovascular therapy should continue to be explored in the treatment of this disease. (Stroke. 2012;43:580-584.)
引用
收藏
页码：580 / 584
页数：5
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