Cardio-Oncology Drug Interactions: A Scientific Statement From the American Heart Association

被引：77

作者：

Beavers, Craig J.

Rodgers, Jo E.

Bagnola, Aaron J.

Beckie, Theresa M.

Campia, Umberto

Di Palo, Katherine E.

Okwuosa, Tochi M.

Przespolewski, Eugene R.

Dent, Susan

机构：

来源：

CIRCULATION | 2022年 / 145卷 / 15期

关键词：

AHA Scientific Statements; cardiovascular system; drug interactions; medical oncology; pharmacokinetics; pharmacology; TYROSINE KINASE INHIBITORS; ACUTE LYMPHOBLASTIC-LEUKEMIA; QT INTERVAL PROLONGATION; BREAST-CANCER PATIENTS; VENOUS THROMBOEMBOLISM; BLOOD-PRESSURE; CLINICAL-PRACTICE; EXPERT CONSENSUS; PHASE-II; CHILDHOOD-CANCER;

D O I：

10.1161/CIR.0000000000001056

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the cardio-oncology population, drug interactions are of particular importance given the complex pharmacological profile, narrow therapeutic index, and inherent risk of therapies used to manage cardiovascular disease and cancer. Drug interactions may be beneficial or detrimental to the desired therapeutic effect. Clinicians in both cardiology and oncology should be cognizant of these potential drug-drug interactions that may reduce the efficacy or safety of either cardiovascular or cancer therapies. These risks can be mitigated through increased recognition of potential drug-drug interaction, use of alternative medications when possible, and careful monitoring. This scientific statement provides clinicians with an overview of pharmacodynamic and pharmacokinetic drug-drug interactions in patients with cancer exposed to common cardiovascular and cancer medications.

引用

页码：e811 / e838

页数：28

共 50 条

[41] Triglycerides and Cardiovascular Disease A Scientific Statement From the American Heart Association [J].

Miller, Michael ;

Stone, Neil J. ;

Ballantyne, Christie ;

Bittner, Vera ;

Criqui, Michael H. ;

Ginsberg, Henry N. ;

Goldberg, Anne Carol ;

Howard, William James ;

Jacobson, Marc S. ;

Kris-Etherton, Penny M. ;

Lennie, Terry A. ;

Levi, Moshe ;

Mazzone, Theodore ;

Pennathur, Subramanian .

CIRCULATION, 2011, 123 (20) :2292-2333

[42] Dietary approaches to prevent and treat hypertension - A scientific statement from the American Heart Association [J].

Appel, LJ ;

Brands, MW ;

Daniels, SR ;

Karanja, N ;

Elmer, PJ ;

Sacks, FM .

HYPERTENSION, 2006, 47 (02) :296-308

[43] Dietary Sugars Intake and Cardiovascular Health A Scientific Statement From the American Heart Association [J].

Johnson, Rachel K. ;

Appel, Lawrence J. ;

Brands, Michael ;

Howard, Barbara V. ;

Lefevre, Michael ;

Lustig, Robert H. ;

Sacks, Frank ;

Steffen, Lyn M. ;

Wylie-Rosett, Judith .

CIRCULATION, 2009, 120 (11) :1011-1020

[44] Statin Safety and Associated Adverse Events: A Scientific Statement From the American Heart Association [J].

Newman, Connie B. ;

Preiss, David ;

Tobert, Jonathan A. ;

Jacobson, Terry A. ;

Page, Robert L., II ;

Goldstein, Larry B. ;

Chin, Clifford ;

Tannock, Lisa R. ;

Miller, Michael ;

Raghuveer, Geetha ;

Duell, P. Barton ;

Brinton, Eliot A. ;

Pollak, Amy ;

Braun, Lynne T. ;

Welty, Francine K. .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2019, 39 (02) :E38-E81

[45] Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association [J].

Yeghiazarians, Yerem ;

Jneid, Hani ;

Tietjens, Jeremy R. ;

Redline, Susan ;

Brown, Devin L. ;

El-Sherif, Nabil ;

Mehra, Reena ;

Bozkurt, Biykem ;

Ndumele, Chiadi Ericson ;

Somers, Virend K. .

CIRCULATION, 2021, 144 (03) :E56-E67

[46] A Primary Care Agenda for Brain Health: A Scientific Statement From the American Heart Association [J].

Lazar, Ronald M. ;

Howard, Virginia J. ;

Kernan, Walter N. ;

Aparicio, Hugo J. ;

Levine, Deborah A. ;

Viera, Anthony J. ;

Jordan, Lori C. ;

Nyenhuis, David L. ;

Possin, Katherine L. ;

Sorond, Farzaneh A. ;

White, Carole L. .

STROKE, 2021, 52 (06) :e295-e308

[47] Electrocardiographic Early Repolarization A Scientific Statement From the American Heart Association [J].

Patton, Kristen K. ;

Ellinor, Patrick T. ;

Ezekowitz, Michael ;

Kowey, Peter ;

Lubitz, Steven A. ;

Perez, Marco ;

Piccini, Jonathan ;

Turakhia, Mintu ;

Wang, Paul ;

Viskin, Sami .

CIRCULATION, 2016, 133 (15) :1520-1529

[48] Revascularization for Renovascular Disease: A Scientific Statement From the American Heart Association [J].

Bhalla, Vivek ;

Textor, Stephen C. ;

Beckman, Joshua A. ;

Casanegra, Ana I. ;

Cooper, Christopher J. ;

Kim, Esther S. H. ;

Luther, James M. ;

Misra, Sanjay ;

Oderich, Gustavo S. .

HYPERTENSION, 2022, 79 (08) :E128-E143

[49] Assessing Cardiac Metabolism A Scientific Statement From the American Heart Association [J].

Taegtmeyer, Heinrich ;

Young, Martin E. ;

Lopaschuk, Gary D. ;

Abel, E. Dale ;

Brunengraber, Henri ;

Darley-Usmar, Victor ;

Des Rosiers, Christine ;

Gerszten, Robert ;

Glatz, Jan F. ;

Griffin, Julian L. ;

Gropler, Robert J. ;

Holzhuetter, Hermann-Georg ;

Kizer, Jorge R. ;

Lewandowski, E. Douglas ;

Malloy, Craig R. ;

Neubauer, Stefan ;

Peterson, Linda R. ;

Portman, Michael A. ;

Recchia, Fabio A. ;

Van Eyk, Jennifer E. ;

Wang, Thomas J. .

CIRCULATION RESEARCH, 2016, 118 (10) :1659-U485

[50] Risk-Based Primary Prevention of Heart Failure: A Scientific Statement From the American Heart Association [J].

Khan, Sadiya S. ;

Breathett, Khadijah ;

Braun, Lynne T. ;

Chow, Sheryl L. ;

Gupta, Deepak K. ;

Lekavich, Carolyn ;

Lloyd-Jones, Donald M. ;

Ndumele, Chiadi E. ;

Rodriguez, Carlos J. ;

Allen, Larry A. .

CIRCULATION, 2025, 151 (20) :e1006-e1026

← 1 2 3 4 5 →