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NMR-based plant metabolomics: where do we stand, where do we go?
被引:268
作者:
Kim, Hye Kyong
[1
]
Choi, Young Hae
[1
]
Verpoorte, Robert
[1
]
机构:
[1] Leiden Univ, Inst Biol, Sect Metabol, NL-2300 RA Leiden, Netherlands
关键词:
MAGNETIC-RESONANCE-SPECTROSCOPY;
IONIC LIQUIDS;
H-1-NMR SPECTROSCOPY;
QUALITY-CONTROL;
IDENTIFICATION;
CLASSIFICATION;
EXTRACTS;
METABONOMICS;
METABOLITES;
RESISTANCE;
D O I:
10.1016/j.tibtech.2011.02.001
中图分类号:
Q81 [生物工程学(生物技术)];
Q93 [微生物学];
学科分类号:
071005 ;
0836 ;
090102 ;
100705 ;
摘要:
NMR-based metabolomics is an important tool for studying biological systems and has been applied in various organisms, including animals, plants and microbes. NMR is able to provide a 'holistic view' of the metabolites under certain conditions, and thus is advantageous for metabolomic studies. To maximize the use of the information obtained, it is also important to create a platform to measure, store and share data. Public databases for storing and sharing information are still lacking for NMR-based metabolomic analysis in plants. Such databases are urgently needed to make metabolic profiling a real omics technology. In addition, to understand metabolic processes in depth, single-cell analysis and the turnover of metabolites in pathways (fluxomics) should be measured.
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页码:267 / 275
页数:9
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