Gaining confidence in high-throughput screening

被引:19
作者
Bibette, Jerome [1 ]
机构
[1] ESPCI ParisTech, UPMC CNRS UMR 7195, Lab Colloides & Mat Divises, F-75231 Paris, France
关键词
MICROFLUIDICS;
D O I
10.1073/pnas.1119350109
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:649 / 650
页数:2
相关论文
共 12 条
[1]   Ultrahigh-throughput screening in drop-based microfluidics for directed evolution [J].
Agresti, Jeremy J. ;
Antipov, Eugene ;
Abate, Adam R. ;
Ahn, Keunho ;
Rowat, Amy C. ;
Baret, Jean-Christophe ;
Marquez, Manuel ;
Klibanov, Alexander M. ;
Griffiths, Andrew D. ;
Weitz, David A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (09) :4004-4009
[2]  
Campbell JB, 2010, IDRUGS, V13, P874
[3]   Drug screening - Beyond the bottleneck [J].
Dove, A .
NATURE BIOTECHNOLOGY, 1999, 17 (09) :859-863
[4]   Navigating chemical space for biology and medicine [J].
Lipinski C. ;
Hopkins A. .
Nature, 2004, 432 (7019) :855-861
[5]   Statistical practice in high-throughput screening data analysis [J].
Malo, N ;
Hanley, JA ;
Cerquozzi, S ;
Pelletier, J ;
Nadon, R .
NATURE BIOTECHNOLOGY, 2006, 24 (02) :167-175
[6]   Novel trends in high-throughput screening [J].
Mayr, Lorenz M. ;
Bojanic, Dejan .
CURRENT OPINION IN PHARMACOLOGY, 2009, 9 (05) :580-588
[7]   High-resolution dose-response screening using droplet-based microfluidics [J].
Miller, Oliver J. ;
El Harrak, Abdeslam ;
Mangeat, Thomas ;
Baret, Jean-Christophe ;
Frenz, Lucas ;
El Debs, Bachir ;
Mayot, Estelle ;
Samuels, Michael L. ;
Rooney, Eamonn K. ;
Dieu, Pierre ;
Galvan, Martin ;
Link, Darren R. ;
Griffiths, Andrew D. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (02) :378-383
[8]   How to improve R&D productivity: the pharmaceutical industry's grand challenge [J].
Paul, Steven M. ;
Mytelka, Daniel S. ;
Dunwiddie, Christopher T. ;
Persinger, Charles C. ;
Munos, Bernard H. ;
Lindborg, Stacy R. ;
Schacht, Aaron L. .
NATURE REVIEWS DRUG DISCOVERY, 2010, 9 (03) :203-214
[9]   Interpreting steep dose-response curves in early inhibitor discovery [J].
Shoichet, Brian K. .
JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (25) :7274-7277
[10]   DISPERSION OF SOLUBLE MATTER IN SOLVENT FLOWING SLOWLY THROUGH A TUBE [J].
TAYLOR, G .
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL AND PHYSICAL SCIENCES, 1953, 219 (1137) :186-203