What, How, and How Much Should Patients with Burns be Fed?

被引:47
作者
Williams, Felicia N. [1 ,2 ]
Branski, Ludwik K. [1 ,2 ]
Jeschke, Marc G. [3 ,4 ]
Herndon, David N. [1 ,2 ]
机构
[1] Shriners Hosp Children, Dept Surg, Galveston, TX 77550 USA
[2] Univ Texas Med Branch, Galveston, TX 77550 USA
[3] Sunnybrook Hlth Sci Ctr, Ross Tilley Burn Ctr, Toronto, ON M4N 3M5, Canada
[4] Univ Toronto, Dept Surg, Div Plast Surg, Toronto, ON M4N 3M5, Canada
关键词
Hypermetabolic response; Burn injury; Trauma; Nutrition; HUMAN GROWTH-HORMONE; RANDOMIZED CONTROLLED-TRIAL; INSULIN-TREATMENT IMPROVES; DOUBLE-BLIND TRIAL; ENERGY-EXPENDITURE; FACTOR-I; GLUCOSE-METABOLISM; MUSCLE PROTEIN; BETA-BLOCKADE; HYPERMETABOLIC RESPONSE;
D O I
10.1016/j.suc.2011.03.002
中图分类号
R61 [外科手术学];
学科分类号
摘要
The hypermetabolic response to severe burn injury is characterized by hyperdynamic circulation and profound metabolic, physiologic, catabolic, and immune system derangements. Failure to satisfy overwhelming energy and protein requirements after, and during, severe burn injury results in multiorgan dysfunction, increased susceptibility to infection, and death. Attenuation of the hypermetabolic response by various pharmacologic modalities is emerging as an essential component of the management of patients with severe burn injury. This review focuses on the more recent advances in therapeutic strategies to attenuate the hypermetabolic response and its postburn-associated insulin resistance.
引用
收藏
页码:609 / +
页数:22
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