Folate use in women with epilepsy: Predictors of adherence in a specialized tertiary outclinic

被引:3
作者
Passarelli, Valmir [1 ]
Visona de Figueiredo, Nathalia Stela [1 ]
Moraes Angst, Debora Bartzen [1 ]
Baldocchi, Meire Argentoni [1 ]
Guimaraes Rocha, Maria Sheila [1 ]
机构
[1] Hosp Santa Marcelina, Dept Neurol, Sao Paulo, SP, Brazil
关键词
Epilepsy; Folate; Women's health; Anticonvulsants; Teratogenesis; Adherence; TECHNOLOGY-ASSESSMENT SUBCOMMITTEE; QUALITY STANDARDS SUBCOMMITTEE; UPDATE MANAGEMENT ISSUES; MAJOR CONGENITAL-MALFORMATIONS; FOLIC-ACID; ANTIEPILEPTIC DRUGS; AMERICAN ACADEMY; PREGNANCY; THERAPEUTICS; NEUROLOGY;
D O I
10.1016/j.yebeh.2014.12.006
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Purpose of the study: The aims of this study were to determine the percentage of women with epilepsy (WWE) taking folic acid (FA) in an outpatient epilepsy tertiary hospital at Sao Paulo, Brazil, and to identify the possible predictors of adherence. Method: Five hundred seventy-six medical records of patients followed in our service were reviewed. Sixty-six WWE using antiepileptic drugs with age between 16 and 52, sexually active but not in menopausal period, not pregnant, and not sterilized or with vasectomized partners underwent direct interviews with a prestructured questionnaire. Logistic regression with clinical and demographic variables using a stepwise method was performed to identify predictable variables of folate use. Results: We found 42.40% of FA intake. Hormonal contraceptive method use was an independent variable negatively associated with adherence to folate. Additionally, educational level was an independent variable positively associated with adherence to folate in WWE above 35 years of age. Conclusion: We found low folate adherence. Improved planning pre-conception for WWE should improve rates of effective folate supplementation. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:74 / 76
页数:3
相关论文
共 33 条
  • [1] [Anonymous], 2012, MAN OR DATN GUIA PRA
  • [2] Effects of Maternal Epilepsy and Antiepileptic Drug Use during Pregnancy on Perinatal Health in Offspring: Nationwide, Retrospective Cohort Study in Finland
    Artama, Miia
    Gissler, Mika
    Malm, Heli
    Ritvanen, Annukka
    [J]. DRUG SAFETY, 2013, 36 (05) : 359 - 369
  • [3] Understanding the information needs of women with epilepsy at different lifestages: results of the 'Ideal World' survey
    Crawford, P
    Hudson, S
    [J]. SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2003, 12 (07): : 502 - 507
  • [4] Czeizel AE, 1996, TERATOLOGY, V53, P345, DOI 10.1002/(SICI)1096-9926(199606)53:6<345::AID-TERA5>3.0.CO
  • [5] 2-Z
  • [6] Federacao Brasileira das Associacoes de Ginecologia e Obstetricia, 2012, GUIA PRAT COND REC S
  • [7] Practice Parameter update: Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): Vitamin K, folic acid, blood levels, and breastfeeding Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society
    Harden, C. L.
    Pennell, P. B.
    Koppel, B. S.
    Hovinga, C. A.
    Gidal, B.
    Meador, K. J.
    Hopp, J.
    Ting, T. Y.
    Hauser, W. A.
    Thurman, D.
    Kaplan, P. W.
    Robinson, J. N.
    French, J. A.
    Wiebe, S.
    Wilner, A. N.
    Vazquez, B.
    Holmes, L.
    Krumholz, A.
    Finnell, R.
    Shafer, P. O.
    Le Guen, C.
    [J]. NEUROLOGY, 2009, 73 (02) : 142 - 149
  • [8] Practice Parameter update: Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): Teratogenesis and perinatal outcomes Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society
    Harden, C. L.
    Meador, K. J.
    Pennell, P. B.
    Hauser, W. A.
    Gronseth, G. S.
    French, J. A.
    Wiebe, S.
    Thurman, D.
    Koppel, B. S.
    Kaplan, P. W.
    Robinson, J. N.
    Hopp, J.
    Ting, T. Y.
    Gidal, B.
    Hovinga, C. A.
    Wilner, A. N.
    Vazquez, B.
    Holmes, L.
    Krumholz, A.
    Finnell, R.
    Hirtz, D.
    Le Guen, C.
    [J]. NEUROLOGY, 2009, 73 (02) : 133 - 141
  • [9] Practice Parameter update: Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): Obstetrical complications and change in seizure frequency Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society
    Harden, C. L.
    Hopp, J.
    Ting, T. Y.
    Pennell, P. B.
    French, J. A.
    Hauser, W. A.
    Wiebe, S.
    Gronseth, G. S.
    Thurman, D.
    Meador, K. J.
    Koppel, B. S.
    Kaplan, P. W.
    Robinson, J. N.
    Gidal, B.
    Hovinga, C. A.
    Wilner, A. N.
    Vazquez, B.
    Holmes, L.
    Krumholz, A.
    Finnell, R.
    Le Guen, C.
    [J]. NEUROLOGY, 2009, 73 (02) : 126 - 132
  • [10] Harden Cynthia L, 2014, Continuum (Minneap Minn), V20, P60, DOI 10.1212/01.CON.0000443837.95260.af