Application of atomic force microscope to the study of bio-cells

被引：1

作者：

Tittmann, B ^{[1
]}

Du, JK ^{[1
]}

Ebert, A ^{[1
]}

Piccione, B ^{[1
]}

机构：

[1] Penn State Univ, Coll Engn, Dept Engn Sci & Mech, University Pk, PA 16802 USA

来源：

Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems IV | 2005年 / 5768卷

关键词：

atomic force microscopy; ultrasonic; elastic properties evaluation; cell;

D O I：

10.1117/12.598871

中图分类号：

TU [建筑科学];

学科分类号：

0813 ;

摘要：

Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used in this work assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both nonviable and viable materials. Improvement of our system for living cell (in a culture) imaging is also discussed.

引用

页码：11 / 18

页数：8

共 13 条

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