Innate lymphoid cells: new insights into function and development

被引:95
作者
Cortez, Victor S. [1 ]
Robinette, Michelle L. [1 ]
Colonna, Marco [1 ]
机构
[1] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63018 USA
基金
美国国家卫生研究院;
关键词
NATURAL-KILLER-CELL; TRANSCRIPTION FACTOR GATA3; T-BET; INTERLEUKIN-22; INFLAMMATION; PROGENITOR; NFIL3; DIFFERENTIATION; MAINTENANCE; ACTIVATION;
D O I
10.1016/j.coi.2015.01.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Here, we illustrate the complexity of ILC subsets and discuss novel functions, focusing on emerging mechanisms of crosstalk with other immune cells and the microbiota. Furthermore, we highlight recent insights into the development of ILCs, including the common pathways they share as well as points of divergence between ILC groups and subsets.
引用
收藏
页码:71 / 77
页数:7
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