High risk of MS in Iranian immigrants in Gothenburg, Sweden

被引：30

作者：

Ahlgren, C. ^{[1
]}

Lycke, J. ^{[1
]}

Oden, A. ^{[2
]}

Andersen, O. ^{[1
]}

机构：

[1] Sahlgrens Univ Hosp, Inst Neurosci & Physiol, S-41345 Gothenburg, Sweden

[2] Chalmers Univ Technol, Dept Math Sci, Inst Stat Math, S-41296 Gothenburg, Sweden

来源：

MULTIPLE SCLEROSIS JOURNAL | 2010年 / 16卷 / 09期

关键词：

Epidemiology; Iran; migration; multiple sclerosis; prevalence; Sweden; MULTIPLE-SCLEROSIS; PREVALENCE; EPIDEMIOLOGY; MIGRATION; ISFAHAN; MIGRANT; AGE;

D O I：

10.1177/1352458510376777

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: In this study we investigated the risk of multiple sclerosis (MS) in migrants who had moved from Iran to Gothenburg, Sweden. Methods: Patients born in Iran were retrieved from a population-based cohort, which included 534 MS and clinically isolated syndrome patients, born 1959-1990, aged 10-39 years at disease onset in Gothenburg. The expected versus observed number of migrants from Iran was calculated. Results: The MS risk in the Iranian migrants in Gothenburg was several times higher than in Isfahan, Iran (hazard ratio 3.88, 95% confidence interval 2.17-6.40). Compared with the general population of Gothenburg, the observed number of 17 Iranian patients was higher than the expected value of 9.89 (hazard ratio 1.72, 95% confidence interval 1.00-2.75). Conclusion: Migration from a medium-risk to a high-risk area may increase the MS risk to that of the high-risk area.

引用

页码：1079 / 1082

页数：4

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