HIV-related neurocognitive impairment - A review

被引:26
作者
Rackstraw, Simon [1 ,2 ]
机构
[1] Mildmay Hosp UK, Dept Med, London, England
[2] Royal London Hosp, Barts & London NHS Trust, London E1 1BB, England
关键词
HIV; cognitive impairment; AIDS; mental health; cognition; HUMAN-IMMUNODEFICIENCY-VIRUS; AIDS DEMENTIA COMPLEX; ACTIVE ANTIRETROVIRAL THERAPY; CENTRAL-NERVOUS-SYSTEM; RAPID SCREENING-TEST; RISK-FACTORS; COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL IMPAIRMENT; CEREBROSPINAL-FLUID; HEPATITIS-C;
D O I
10.1080/13548506.2011.579992
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Neurocognitive impairments following central nervous system opportunistic infections and HIV-associated dementia (HAD) were common clinical features of HIV infection prior to anti-retroviral therapy. As HIV infection has evolved from an invariably fatal disease with a poor prognosis to a condition requiring long-term management, HIV-related neurocognitive disorders have been the subject of increasing research. This review will examine the recent changes in the understanding of the HIV-associated neurocognitive disorders (HAND) including the changing epidemiology, risk factors associated with its development, methods for screening for the disorders and evolving treatment options.
引用
收藏
页码:548 / 563
页数:16
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