Causal mechanisms in the clinical course and treatment of back pain

被引：53

作者：

Lee, H. ^{[1
,2
,3
,4
]}

Mansell, G. ^{[5
]}

McAuley, J. H. ^{[2
,3
]}

Kamper, S. J. ^{[4
,6
]}

Hubscher, M. ^{[2
]}

Moseley, G. L. ^{[7
]}

Wolfenden, L. ^{[1
,8
]}

Hodder, R. K. ^{[1
,8
]}

Williams, C. M. ^{[1
,4
,6
]}

机构：

[1] Univ Newcastle, Hunter Med Res Inst, Sch Med & Publ Hlth, Callaghan, NSW, Australia

[2] Neurosci Res Australia NeuRA, Sydney, NSW, Australia

[3] Univ New South Wales, Prince Wales Clin Sch, Sydney, NSW, Australia

[4] Ctr Pain Hlth & Lifestyle, Sydney, NSW, Australia

[5] Keele Univ, Res Inst Primary Care & Hlth Sci, Keele ST5 5BG, Staffs, England

[6] Univ Sydney, George Inst Global Hlth, Sydney, NSW, Australia

[7] Univ South Australia, Sansom Inst Hlth Res, Adelaide, SA, Australia

[8] Hunter New England Local Hlth Dist, Hunter New England Populat Hlth, New Lambton Hts, NSW, Australia

来源：

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2016年 / 30卷 / 06期

基金：

英国医学研究理事会;

关键词：

Back pain; Mediation analysis; Mechanism; Causal inference; MEDIATION ANALYSIS; SELF-EFFICACY; SENSITIVITY-ANALYSIS; PRIMARY-CARE; IMPLEMENTATION; IDENTIFICATION; DISABILITY; MOVEMENT; OUTCOMES; PEOPLE;

D O I：

10.1016/j.berh.2017.04.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In recent years, there has been increasing interest in studying causal mechanisms in the development and treatment of back pain. The aim of this article is to provide an overview of our current understanding of causal mechanisms in the field. In the first section, we introduce key concepts and terminology. In the second section, we provide a brief synopsis of systematic reviews of mechanism studies relevant to the clinical course and treatment of back pain. In the third section, we reflect on the findings of our review to explain how understanding causal mechanisms can inform clinical practice and the implementation of best practice. In the final sections, we introduce contemporary methodological advances, highlight the key assumptions of these methods, and discuss future directions to advance the quality of mechanism related studies in the back pain field. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：1074 / 1083

页数：10

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